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Medicine UWorld Exam Questions and Answers 100% Solved | Graded A+

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Medicine UWorld Exam Questions and Answers 100% Solved | Graded A+ A 9 yo boy presents with asymptomatic tongue nodules that are firm and rubbery. They do not disturb his taste or swallowing. He is also very tall for his age and with long fingers and arms. Dx and increased risk for what? - MEN...

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  • November 20, 2024
  • 124
  • 2024/2025
  • Exam (elaborations)
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©JOSHCLAY 2024/2025. YEAR PUBLISHED 2024.
Medicine UWorld Exam Questions and

Answers 100% Solved | Graded A+


A 9 yo boy presents with asymptomatic tongue nodules that are firm and

rubbery. They do not disturb his taste or swallowing. He is also very tall for

his age and with long fingers and arms. Dx and increased risk for what? -

✔✔MEN2B



- increased risk for medullary thyroid cancer and pheo

What is the typical management of MEN2B? - ✔✔prophylactic

thyroidectomy <1 year of age and chronic screening for pheo

How does sepsis affect right atrial and pulmonary capillary wedge

pressure? - ✔✔peripheral vasodilation -> decreased systemic vascular

resistance -> decreased low right atrial pressure (less blood coming back)

and decreased PCWP

What causes bounding peripheral pulses in the setting of sepsis? -

✔✔decreased systemic vascular resistance causes and increase in stroke

,©JOSHCLAY 2024/2025. YEAR PUBLISHED 2024.
volume, leading to an increased pulse pressure (difference between

systolic and diastolic pressure)

What is Ludwig angina? - ✔✔rapidly progressive cellulitis of the

submandibular and sublingual spaces most like 2/2 to infection of

mandibular molars

What is the most deadly aspect of Ludwig angina? - ✔✔airway obstruction

39 yo pt with a history of Roux-en-Y gastric bypass presents with 2 mo of

5-6 large volume greasy-stools/day. She has has macrocytic anemia and

evidence of malabsorption. Dx? - ✔✔small intestine bacterial overgrowth

What tests can help diagnose small intestine bacterial overgrowth? -

✔✔carb breath tests: lactulose, glucose, to measure the hydrogen

production of intestinal flora

What is the pathophysiology of Dumping Syndrome? - ✔✔post-gastric

bypass complication that occurs with high-carb foods rapidly emptied into

small bowel -> osmotic shifts -> diarrhea.



no associated stearhea or vitamin deficiencies

,©JOSHCLAY 2024/2025. YEAR PUBLISHED 2024.
Homeless man presents with CVA tenderness, blood in urine, and calcium

oxalate crystals in the urine. Labs show an AKI. Dx? - ✔✔Ethylene

glycole/antifreeze intoxication

What is the treatment of ethylene glycol/antifreeze intoxication? -

✔✔Fomepizole - competitive inhibitor of alcohol dehydrogenase to prevent

further breakdown of ethnalol



hemodialysis may be required

Injestion of what toxic alcohols cause an increased anion gap metabolic

acisodid? - ✔✔methanol and ethylene glycol/antifreeze ingestion

Homeless man presents with visual symptoms, turns out to be a central

scotoma and confusion. His pupils do not constrict to light. Labs show an

increased anion gap metabolic acidosis. Dx? - ✔✔Methanol intoxication

Homeless man presents with lethargy and a discongugate gaze. He has an

absent ciliary reflex. Dx? - ✔✔Isopropyl alcohol intoxication

What risk factor has the strong associated with both ischemic and

hemorrhagic stroke? - ✔✔HTN (4x the risk)

26 yo with prednisone-controlled lupus presents with 1 wk Hx of fevers,

chills, and a dry cough. Her O2 sat is 86% on RA an her LDH is increased.

, ©JOSHCLAY 2024/2025. YEAR PUBLISHED 2024.
CXR shows diffuse reticular infiltrates. Dx and treatment? -

✔✔Pneumocystis Jiroveci Pneumonia due to immunosuppression.



Tx with Bactrim

What is the treatment of PCP pneumonia? - ✔✔bactrim



must also assess immune status

39 yo male that returned from a 2 week trip to India presents with 4 days of

nausea, loss of appetite, and mild RUQ pain. Labs show increased total

bilirubin and very high transaminases. Most likely Dx? - ✔✔Hep A

What combination of alcohol and what substances can result in acute

erosive gastropathy? - ✔✔Alcohol + cocaine (vasoconstriction) and

aspiring

What cardiac abnormality can be caused directly due to an implantable

pacemaker or cardioverter-defibrillator? - ✔✔tricuspid regurgitation

because it travels from the right atrium, through the tricuspid, and into the

right ventricle

What is involved in the initial evaluation of lupus? - ✔✔CBC, renal function

studies, serum complement (C3, C4)

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