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Ciulla - ISBB Questions, Answers, Rationales | Latest Updates | study Guide | Complete Solutions.
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Ciulla: ISBBStudy online at https://quizlet.com/_fw14xy
1. 1. Color Plate 21 ("Y" shaped, right portion of the "Y" A. Fab fragment
prong), depicts a monomeric immunoglobulin mol-
ecule. The portion of the molecule indicated by the
dotted red circle and the red arrow is called the:
A. Fab fragment
B. Fc fragment
C. Heavy chain
D. Hinge region
2. 2. A hapten is: D. A deter-
A. Half of an immunoglobulin molecule minant capable
B. A carrier molecule for an antigen that is not anti- of stimulating an
genic alone immune resonse
C. An immunoglobulin functional only in the presence only when bound
of complement to a carrier
D. A determinant capable of stimulating an immune
resonse only when bound to a carrier
3. 3. Which of the following is characterstic of B cells? C. Contain surface
A. Phagocytic immunolobulins
B. Participate in antibody-dependent cellular cytotox-
icity (ADCC) reactions
C. Contain surface immunolobulins
D. Secrete the C5 component of complement
4. 4. A lymphokine is: B. A soluble me-
A. A soluble mediator produced by granulocytes and diator produced by
affecting lymphocytes lymphocytes
B. A soluble mediator produced by lymphocytes
C. A soluble mediator produced by plasma cells
D. An antibody that reacts with lymphocytes
5. 5. Monocytes and macrophages play a major role A. Fc region
in the mononuclear phagocytic system. For an an-
tibody-coated antien to be phagocytized, what part
of the antibody molecule fits into a receptor on the
phagoytic cell?
A. Fc region
B. Fab region
, Ciulla: ISBB
Study online at https://quizlet.com/_fw14xy
C. Hinge region
D. Variable region
6. 6. Cell-mediated immunity is primarily mediated by: B. T helper cells
A. B cells
B. T helper cells
C. Plasma Cells
D. Dendritic cells
7. 7. The HLA complex is located primarily on: B. Chromosome 6
A. Chromosome 3
B. Chromosome 6
C. Chromosome 9
D. Chromosome 17
8. 8. HLA antigens are found on: A. All nucleated
A. All nucleated cells cells
B. Red Blood cells only
C. solid tissue only
D. White blood cells only
9. 9. Which of the following is more likely to be diagnos- A. A total acute an-
tic of an acute infection? tibody titer of 2 fol-
A. A total acute antibody titer of 2 followed by a lowed by a conva-
convalescent titer of 16 lescent titer of 16
B. A total acute antibody titer of 80
C. A total antibody titer of 80
D. An IgG antibody titer of 80
10. 10. A young woman shows increased susceptibility to C. She has de-
pyogenic infection. Upon assay, she show a low level creased produc-
of C3. Which of the following statements is probably tion of C3
true?
A. She has an autoimmune disease with continual
antigen-antibody activity causing consumption of C3
B. She has DiGeorge syndrome
C. She has decreased production of C3
D. She may produce an inactive form of C2, a precur-
sor of C3.
, Ciulla: ISBB
Study online at https://quizlet.com/_fw14xy
11. 11. What is the predominant type of antibody found in D. Maternal IgG
the serum of neonates born after full-term gestation?
A. Infant IgA
B. Infant IgG
C. Infant IgM
D. Maternal IgG
12. 12. An improtant part of the nonspecific immune re- C. Complement
sponse is (are): cascade
A. B cells
B. Basophils
C. Complement cascade
D. Cytotoxic T lymphocytes
13. 13. The major class of immunoglobulin found in adult C. IgG
human serum is:
A. IgA
B. IgE
C. IgG
D. IgM
14. 14. Which class of immunoglobulin possesses delta B. IgD
heavy chains?
A. IgA
B. IgD
C. IgE
D. IgG
15. 15. Which class of immunoglobulin possesses 10 D. IgM
antigenic binding sies?
A. IgA
B. IgD
C. IgG
D. IgM
16. 16. Color plate 22 (center of a dimeric IgA mole- A. J-piece
cule) represents a dimeric IgA molecule. The struc-
ture printed in red and indicated by the red arrow is
called the:
A. J-piece
, Ciulla: ISBB
Study online at https://quizlet.com/_fw14xy
B. Hinge region
C. Heavy Chain
D. Light Chain
17. 17. Which class of immunoglobulin binds to ba- C. IgE
sophils ad mast cells to mediate immediate hypersen-
sitivity reactions?
A. IgA
B. IgD
C. IgE
D. IgG
18. 18. Type I hypersensitivity is: D. An immediate
A. Associated with complement mediated cell lysis allergic reaction
B. Due to immune complex deposition
C. Mediated by activated macrophages
D. An immediate allergic reaction
19. 19. When performing the enzyme-muliplied im- C. Competes
munoassay technique (EMIT), how is the ligand in the with enzyme-la-
patient's serum detected? beled antigen for
A. Agglutinates by binding to antiboyd-coated latex binding to a specif-
beads ic antibody
B. Binds to enzyme-labeled antibody
C. Competes with enzyme-labeled antigen for binding
to a specific antibody
D. Forms antibody-antigen complex and precipitates
20. 20. Severe combined immunodeficiency (CID) is an: C. Immunodefi-
A. Immunodeficiency with decreased B cells and neu- ciency with de-
trophils creased or dys-
B. Immunodeficiency with lymphocytopenia and functional T and B
eosinophilia cells
C. Immunodeficiency with decreased or dysfunction-
al T and B cells
D. Immunodeficiency with decreased lymphocytes
and decreased complement concentration
21. 21. An example of immune injury due to the deposi- A. Acute glomeru-
tion of antigen-antibody complexes is: lonephritis
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