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TESTBANK l
TietzFundamentalsOf
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CLINICAL CHEMISTRY AND
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l MOLECULAR DIAGNOSTICS l
7th Edition By Carl A. Burtis
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TESTBANK l
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,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 7th Edition Test Bank
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Table of contents:
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I. Principles Of Laboratory Medicine
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Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
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Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
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Chapter 3. Clinical Evaluation of Methods
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Chapter 4. Evidence-Based Laboratory Medicine
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Chapter 5. Establishment and Use of Reference Values
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Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
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Chapter 7. Quality Management
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II. Analytical Techniques And Instrumentation
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Chapter 8. Principles of Basic Techniques and Laboratory Safety
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Chapter 9. Optical Techniques
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Chapter 10. Electrochemistry and Chemical Sensors
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Chapter 11. Electrophoresis
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Chapter 12. Chromatography
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Chapter 13. Mass Spectrometry
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Chapter 14. Enzyme and Rate Analyses
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Chapter 15. Immunochemical Techniques
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Chapter 16 Automationl l
Chapter 17. Point-of-Care Instrumentation
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III. Analytesl
Chapter 18. Amino Acids, Peptides, and Proteins
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Chapter 19. Serum Enzymes
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Chapter 20. Tumor Markers and Cancer Genes
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Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
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Chapter 22. Carbohydrates
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Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
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Chapter 24. Electrolytes and Blood Gases
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Chapter 25. Hormones l l
Chapter 26. Catecholamines and Serotonin
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Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
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Chapter 28. Hemoglobin, Iron, and Bilirubin
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Chapter 29. Porphyrins and Porphyrias
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Chapter 30. Therapeutic Drugs and Their Management
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Chapter 31. Clinical Toxicology
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Chapter 32. Toxic Metals
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IV. Pathophysiology
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Chapter 33. Diabetes l l
,Chapter 34. Cardiovascular Disease
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Chapter 35. Kidney Disease
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Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
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Chapter 37. Liver Disease
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Chapter 38. Gastrointestinal and Pancreatic Diseases
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Chapter 39. Disorders of Bone and Mineral Metabolism
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Chapter 40. Disorders of the Pituitary Gland
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Chapter 41. Disorders of the Adrenal Cortex
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Chapter 42. Thyroid Disorders
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Chapter 43. Reproduction-Related Disorders
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Chapter 44. Pregnancy and Prenatal Testing
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Chapter 45. Newborn Screening and Inborn Errors of Metabolism
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Chapter 46. Pharmacogenetics
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V. Molecular Diagnostics
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Chapter 47. Principles of Molecular Biology
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Chapter 48. Nucleic Acid Techniques and Applications
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Chapter 49. Genomes and Nucleic Acid Alterations
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, Tietz Fundamentals of Clinical Chemistry and MolecularDiagnostics, 7e Burtis Test Bank
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Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory MedicineTest Bank
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MULTIPLE CHOICE l
1. An individual working in a clinical chemistry laboratory is married to a sales representative
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who works for a company that sells chemistry laboratory supplies. When the laboratory
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manager requests a list of needed supplies, cost of supplies, and vendors, this individual only
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recommends the spouse’s company as the vendor. This is considered to be a(n):
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a. accounting issue. l
b. possible conflict of interest. l l l
c. maintenance of confidentiality issue. l l l
d. problem with resource allocation. l l l
ANS: B l
Concern has been raised over the interrelationships between practitioners in the medical field and
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commercial suppliers of drugs, devices, equipment, etc., to the medical profession.
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Similarly, relationships have been scrutinized between clinical laboratorians and manufacturers
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and providers of diagnostic equipment and supplies. These concerns led the National Institutes
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of Health (NIH) in 1995 to require official institutional review of financial disclosure by
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researchers and management of situations in which disclosure indicates potential conflicts of
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interest.
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DIF: 1 REF: Page 4-5 l l l OBJ: 6 | 7 l l l
2. A patient visits her physician stating that her prescribed painkiller is not working to reduce
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the pain following her recent surgery. A friend of the patient claims that the same painkiller
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“worked wonders” to reduce her pain after the same surgery. The physician states that the
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difference in the effect of the drug might be caused by
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pharmacogenetics.
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a. epidemiology
b. an inherited disease l l
c. a conflict of interest l l l
d. a genetic variation in drug-metabolizing enzymes
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ANS: D l
Pharmacogenetics is the study of the genetic variation of drug metabolism between l l l l l l l l l l l
individuals.
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DIF: 1 REF: Page 3 l l l OBJ: 1 l
3. John works in a molecular diagnostics laboratory and receives a blood sample that has the
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name of a close friend printed on the bar-coded label. The genetic test that is ordered on the
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friend’s sample would provide diagnostic information about a disorder that has a poor
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prognosis, and the test is usually performed by John. He asks a fellow employee to analyze
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the sample for him and not divulge the results. This ethical issue concerns:
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a. confidentiality of patient genetic and medical information. l l l l l l
b. a conflict of interest.
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c. resource allocation. l
d. diagnostic accuracy. l
