NRSG 357: Cancer Care – Questions & Answers (100%)
What is interphase? Right Ans - Period where the cell spends most of its
time, primarily have cell growth occur, but no cell division, this is where most
cells live, expect cancer
What is G1 phase? Right Ans - the first part of interphase, longest phase of
the cell cycle, where we produce extra organelles such as ribosomes and
proteins
What is G0 phase? Right Ans - no more cell division-cells go here
sometimes instead of S
What is S phase? Right Ans - synthesis phase, DNA synthesis-this is where
the DNA replicates
What is G2 phase? Right Ans - another growth phase where we are more
directly preparing for mitosis
What is mitosis? Right Ans - active cell division
What are cyclin-dependent kinases (CDK)? Right Ans - -Protein kinases
that regulate the cell cycle (mitosis; kinases add a phosphate group);
-works together with cyclins;
-always present in a cell, but their default function is to be inactive
How are CDK activated? Right Ans - -Cyclin proteins
-specific cyclins made at specific times
What happens when the tumor suppressor loses its function? Right Ans - -
Tumors are able to grow because the cell cycle is not controlled
-Cancer. Tumors have a defect in p53. P21 does not lead to cancer when it is
defected.
What is hyperplasia? Right Ans - Increase in the amount of organic tissue
that results from cell proliferation
What is hypertrophy? Right Ans - The increase in the volume of an organ or
tissue due to the enlargement of its component cells
, What is dysplasia? Right Ans - Presence of cells of an abnormal type within
a tissue which can signify cancer
What is metaplasia? Right Ans - The reversible transformation of one
differentiated cell type to another
What is apoptosis? Right Ans - The normal occurrence of cellular death
What is contact inhibition? Right Ans - Regulatory mechanism that
functions to keep cells growing into a layer one cell thick
What is angiogenesis? Right Ans - The development of new blood vessels
What is protoonocgene? Right Ans - Normal cell genes that regulate the
normal cell processes
What is onocgene? Right Ans - Tumor inducing genes
What is tumor suppressor gene? Right Ans - regulate cell growth
What is neoplasm? Right Ans - A new growth of abnormal tissue that is
uncontrolled and progressive
What is a neoplastic? Right Ans - cancer
What is cancer? Right Ans - -A group of diseases characterized by
uncontrolled and unregulated cell growth
-is an umbrella term
-ALL are genetic (a mutation on the cells DNA); is genetic but not always
hereditary
Who does cancer affect? Right Ans - affects all ages, ethnic groups, both
genders
Is cancer hereditary? Right Ans - -Hereditary NOT ALWAYS (less common;
5-10%);
-if it is inherited will develop cancer at an earlier age
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