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Hematology and Oncology PANCE&PANRE Exam With Complete Solutions Latest Update
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Hematology and Oncology PANCE&PANRE Exam WithComplete Solutions Latest Update
Auer rods on peripheral smear indicate.? - ANWER acute myeloblastic leukemia (AML)
60 year old male with severe anemia, decreased neutrophil count and small, abnormal B
lymphocytes in the bone marrow (>30%) with levels at 90,000 per cubic millimeter.
Painless cervical lymphadenopathy and hepatosplenomegaly. Likely diagnosis? -
ANWER Chronic lymphocytic leukemia (CLL)
Bone marrow aspiration and biopsy show that dividing marrow cells have the
Philadelphia (Ph) chromosome. Most likely diagnosis? - ANSWER CML Chronioc
myeloblastic leukemia
Follicular, cleaved cell, lymphocytic, histolytic - ANSWER Hodgkins Lymphoma
Reed Sternberg cell - ANSWER Hodgkin's lymphoma
Plasma cells, monoclonal protein - ANSWER Multiple myeloma
Which of the following conditions presents abnormal monoclonal protein, anemia and
lytic bony lesions? - ANSWER Multiple myeloma
30 yr old white male with a 3-month history of painless enlargement of bilateral cervical
lymph nodes, fever, and night sweats. Likely diagnosis? - ANSWER Hodgkin's disease
What hematologic measurement is abnormal in chronic heavy alcohol use? - ANSWER
Mean corpuscular volume
, Most frequent cause of B12 deficiency in patients with classic pernicious anemia -
ANSWER Lack of intrinsic factor
Thalassemia Anemia - what is the cause of the anemia? ANSWER Shortened life span of
RBCs
adolescent black female with painful bones and joints. CBC= severe anemia with
elevated WBC and platelet counts. Diagnosis? ANSWER Sickle cell disease
What 2 tests confirm the diagnosis of homozygous sickle cell disease? ANSWER
Peripheral smear and hemoglobin electrophoresis
Most useful test to differentiate megaloblastic from nonmegaloblastic macrocytic
anemia - ANSWER Peripheral smear
What is the most common initial presentation of sickle cell disease? - ANSWER Failure to
thrive in a child at risk
4 year old with fever, bleeding, bone pain, generalized lymphadenopathy, splenomegaly,
hepatomegaly. CBC shows anemia, leukocytosis (100,000 immature WBC) and
thrombocytopenia. Prognosis is good. Likely diagnosis? - ANSWER Acute lymphocytic
leukemia
Type of anemia, with small red blood cells, MCV <76 - ANSWER Microcytic anemia
Name the classic types of microcytic anemia - ANSWER Iron deficiency anemia,
thalassemia, sideroblastic anemia, anemia of chronic disease, lead poisoning
Type of anemia, with large red blood cells, MCV >100 - ANSWER Macrocytic anemia
Causes of megaloblastic anemia - ANSWER B12 (cobalamine) deficiency, folate
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