DNP Pharmacology-
Muskuloskeletal Practice
Questions fully solved &
updated 2025
What is the mechanism of action of allopurinol? - answer acts directly on
the purine metabolism thus reducing uric acid production
When prescribing any headache therapy, appropriate use of medications
needs to be discussed to prevent medication-overuse headaches. A clinical
characteristic of medication-overuse headaches is that they: - answer
Recur when medication wears off
Sallie has been taking 10 mg per day of prednisone for the past 6 months.
She should be assessed for: - answer Osteoporosis
The goal of treatment of acute pain is: - answer Reduction or elimination
of pain with minimum adverse reactions
Melanie presents to your practice with complaint of migraines. After a
thorough health history, you decide to use serotonin receptor agonists or
"triptans". These medications are contraindicated in patients with: -
answer pregnancy, uncontrolled HTN, and CAD
Acetaminophen is used to treat? - answer A. Pain
B. Fever
C. Inflammation
D. Only A & B (ANSWER)
Patient education when prescribing colchicine includes: - answer
Colchicine always causes some degree of diarrhea.
, When prescribing for migraines, patient education includes: - answer
Stress reduction and regular sleep are integral to migraine treatment.
What is the established frequency of repeating DEXA imaging after stating
bisphosphonates? - answer There is no evidence-based time line for
monitoring after the first 2 years
Preventative therapy for cluster headaches includes: - answer Ergotamine
nightly before bed
Sallie has been diagnosed with osteoporosis and is asking about the "once
a month" pill to treat her condition. How do bisphosphonates treat
osteoporosis? - answer By reducing bone resorption and inhibiting
osteoclastic activity
Selective estrogen receptor modifiers (SERMs) treat osteoporosis by
selectively: - answer Selectively acting on the estrogen receptors in the
bone
Vicky, age 56 years, comes to the clinic requesting a refill of her Fiorinal
(aspirin and butalbital) that she takes for migraines. She has been taking
this medication for over 2 years for migraines and states one dose usually
works to abort her migraine. What is the best care for her? - answer
Assess how often she is using Fiorinal and refill her medication.
The patient you are seeing today has been recently started on a
medication for gout, she is complaining of a new skin rash. Which of the
following Gout medications can cause a maculopapular skin rash that
sometimes can be scaly or exfoliative especially in the presence of renal
disorders. - answer allopurinol
Which two gout medications work by inhibiting xanthine oxidase, the
enzyme responsible the conversion of hypoxanthine and xanthine to uric
acid? - answer allopurinol and febuxostat (Uloric)
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