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PHAR 100 MIDTERM EXAM QUESTIONS AND ANSWERS
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PHAR 100 MIDTERM EXAM QUESTIONS AND ANSWERS
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PHAR 100 MIDTERM EXAM QUESTIONSAND ANSWERS
What iiis iithe iimajor iiexcitatory iineurotransmitter iiin iithe iibrain? ii- iiAnswers ii-glutamate
what iiis iithe iiis iithe iiprimary iiinhibitory iineurotransmitter iiin iithe iiCNS? ii- iiAnswers ii-
GABA
How iido iibenzodiazepines iireduce iian iiathletes iianxiety? ii- iiAnswers ii-they iiincrease
iiCNS iidepression
which iione iiof iithe iistatements iilisted iiis iicorrect iiin iirelation iito iisedative-hypnotics?
b) iizopiclone, iia iibenzodiazepine iilike iidrug, iiis iia iiGABA iireceptor iiagonist iiwhich iihas
iiminimal iieffects iion iisleep iipatterns ii
a) iiflumazenil iiis iia iiGABA iireceptor iiagonist
c) iibenzodiazepines iiact iion iiserotonin iireceptors ii
d) iibarbiturates iiare iirarely, iiif iiever, iiassociated iiwith iilethality ii- iiAnswers ii-a) iiyes,
iiZopiclone iistimulates iiGABA iireceptors, iiit iihas iiless iieffects iion iisleep iipatterns iithan
iiregular iibenzodiazepines ii
b) iino, iiit iiis iia iibenzodiazepine iiantagonist ii
c) iino, iithey iiact iion iiGABA iireceptors. iiBuspirone iiacts iion iiserotonin iireceptors ii
d) iithey iiare iiactually iithe iisedative-hynotic iithe iimost iiassociated iiwith iilethality
which iione iiof iithe iioptions iilisted iiis iia iipharmacological iiproperty iiof iithe
iibenzodiazepines?
a) iithe iibenzodiazepines iioften iicause iilethality ii
b) iithey iido iinot iiexhibit iicross iitolerance iiwith iibarbiturates ii
c) iitolerance iioccurs iito iithe iisedative iiand iihypnotic iieffects iiof iithem
d) iiaddiction iidoes iinot iidevelop iito iithem ii- iiAnswers ii-c) iitolerance iidoes iinot iiappear iito
iibe iia iiproblem iifor iithe iiclinical iiuse iiof iithese iidrugs, iihowever iiit iican iidevelop iito iithe
,iisedative iieffects iiand iiimpairment iiof iicoordination, iithe iianxiolytic iieffects iior iithe
iieuphoric iieffects
one iipharmacological iiproperty iiof iialcohol iiis iithat iiit iiis:
a) iiclassified iias iia iiCNS iistimulant ii
b) iitransferred iiacross iithe iiplacenta iiwith iisome iidifficulty ii
c) iirapidly iiabsorbed iifrom iithe iistomach iiand iiintestine ii
d) iiable iito iiproduce iitolerance iibut iinot iiwithdrawal ii- iiAnswers ii-c) iialcohol iiis iirapidly
iiabsorbed iifrom iithe iistomach ii(20%) iiand iiintestine ii(80%)
which iistep iiof iialcohol iimetabolism iiis iiconsidered iirate-limiting
a) iiconversion iiof iialcohol iito iiacetaldehyde iiby iialdehyde iidehydrogenase ii
b) iiconversion iiof iiacetaldehyde iito iiacetate iiby iialdehyde iidehydrogenase ii
d) iiconversion iiof iiacetate iito iicarbon iidioxide iiand iiwater iiby iia iinumber iiof iitissues ii-
iiAnswers ii-a) ii
alcohol iidehydrogenase iiis iithe iirate iilimiting iistep iiin iiethanol iimetabolism
the iimechanism iiof iiaction iiof iicannabis iiis iibest iidescribed iias?
a) iicannabis iibinds iito iiCB2 iireceptors iion iipostsynaptic iineuronal iimembranes iiin iithe
iibrain ii
b)cannabis iibinds iito iiCB1 iireceptors iion iipostsynaptic iineuronal iimembranes iiin iithe
iiperiphery ii
c) iicannabis iibinds iito iiCB1 iireceptors iion iipresynaptic iineuronal iimembranes iiin iithe
iibrain ii
d) iicannabis iibinds iito iiCB2 iireceptors iion iipresynaptic iineuronal iimembranes iiin iithe
iibrain iistem ii- iiAnswers ii-c) ii
the iimechanism iiof iiaction iiof iicannabis iiinvolves iiCB1 iireceptors iion iipresynaptic
iineuronal iimembranes
which iireceptor iidoes iiTHC iibind iito?
a) iidopamine
,b) iicannabinoid
c) iialpha
d) iibeta ii- iiAnswers ii-b)
what iiis iiusually iithe iicause iiof iideath iiin iiopioid iioverdose? ii- iiAnswers ii-depression iiof
iirespiration
what iiare iithe iithree iitherapeutic iiuses iiof iiopioids? ii- iiAnswers ii-relief iiof iisevere iipain ii
treatment iiof iidiarrhea
cough iisuppression
why iiis iimethadone iiused iiin iithe iitreatment iiof iiOUD? ii
a) iiin iicombination iiwith iinaloxone, iiit iiprevents iithe iibinding iiof iiopioids iito iithe iiopioid
iireceptor
b) iiit iiis iimore iieffective iithan iiillicit iiopioids iiin iirelieving iipain, iithus iideterring iiillicit iiopioid
iiuse ii
c) iiit iiblocks iimu iiopioid iireceptors iiin iithe iicase iiof iioverdose, iipreventing iirespiratory
iidepression
d) iiit iitransfers iiindividuals iiwith iian iiOUD iito iian iiopioid iithat iiis iilong-acting iiand iidoesn't
iicause iieuphoria iiin iistabilized iipatients ii- iiAnswers ii-d) iimethadone iiis iiused iito iitreat
iiOUDs iibecause iiit iidoesn't iicause iieuphoria
which iione iiof iithe iioptions iilisted iiis iian iiadverse iieffect iiof iiopioids?
a) iimydriasis ii(dilation iiof iipupil)
b) iirespiratory iidepression
c) iidiarrhea ii
d) iihigh iibody iitemperature ii- iiAnswers ii-b)
how iihas iihistorical iiuse iiof iichemicals iicontributed iito iithe iiadvancement iiof
iipharmacology?
a)weaponized iipoisons iiat iihigher iidoses iiwere iifound iito iihave iitherapeutic iieffects ii
, b) iiuse iiof iisulfa iidrugs iiled iito iithe iidevelopment iiof iithe iifirst iisynthetic iiantibacterial
iicompounds
c) iihistorical iiuse iiof iinatural iicompounds iiat iiultra iilow iidoses iiresulted iiin iitherapeutic
iieffects ii
d)extraction iiof iichemical iicompounds iifrom iiman-made iipoisons iithat iiresulted iiin iia
iilarge iiscale iihuman iiepidemics iiled iito iithe iidiscovery iiof iidrugs iistill iiused iitoday ii-
iiAnswers ii-b) iisulfa iidrugs iiwere iithe iifirst iisynthetic iidrugs iiused iito iitreat iibacterial
iidisease iiand iiled iito iithe iidevelopment iiof iiantibacterial iicompounds
which iione iiof iithe iihistorical iidrugs iilisted iiis iistill iicommonly iiused iitherapeutically
iitoday?
a) iiMa iihuang
b) iiLSD
c) iiMorphine
d) iiCurare ii- iiAnswers ii-c)
phase ii3 iiclinical iitrials iican iiemploy iia iiplacebo. iiwhich iiof iithe iistatements iimost
iiaccurately iidescribes iia iiplacebo?
a) iian iiinert iisubstance iimasquerading iias iia iidrug ii
b) iiplacebo iitherapy iiprovides iisatisfactory iirelief iiin iiapproximately ii55% iiof iisick
iianxious iipatients
c) iithe iilikelihood iiof iiplacebo iieffects iiis iigreater iiin iinormal iivolunteers iithan iiin iisick
iianxious iipatients iiunder iistress
d) iiplacebo iiresponses iiare iiwell iiunderstood iiand iithus iineed iinot iibe iicontrolled iiin iia
iiphase ii3 iistudy ii- iiAnswers ii-a) iia iiplacebo iidoes iinot iiactually iicontain iiany iiactive iidrug
the iisound iiand iilong iiestablished iiway iito iiprove iior iidisprove iithe iivalue iiof iia iinew
iimedication iior iitreatment iiis iia iirandomized iicontrolled iitrial. iithis iimeans iithat:
a) iipatients iiare iiselected iiand iiassigned iito iivarious iitest iigroups iibased iion iitheir
iicharacteristics ii
b) iiall iipatients iireceive iithe iinew iidrug iior iithe iicontrol iidrug ii(gold-standard iior iiplacebo)
iion iialternating iidays
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