Exam (elaborations)
PHAR 100 Final exam questions and answers
- Course
- Institution
PHAR 100 Final exam questions and answers
[Show more]
Content preview
PHAR 100 Final exam questions andanswers
Path iiof iidrug iifrom iiwhen iiit iienters iito iiexits iithe iibody ii- iiAnswers ii-1. iiAbsorption
2. iiDistribution
3. iiMetabolism
4. iiExcretion
Absorption ii- iiAnswers ii-the iimovement iiof iithe iidrug iifrom iithe iisite iiof iiadministration
iiinto iithe iibloodstream
Distribution ii- iiAnswers ii-the iimovement iiof iia iidrug iifrom iithe iiblood iito iithe iisite iiof
iiaction iiand iiother iitissues
Metabolism ii- iiAnswers ii-the iiconversion iiof iia iidrug iito iia iidifferent iichemical iicompound.
Excretion ii- iiAnswers ii-moving iiof iithe iidrug iiand iiits iimetabolites iiout iiof iithe iibody
Routes iiof iidrug iiadministration ii- iiAnswers ii-1. iiTopical
- iiOn iithe iiskin
-Transdermal
-Inhalation
2. iiEnteral
-Oral
-Suppository
-Buccal
3.Parenteral
-IV
-IM
-Subcutaneous
Why iiand iihow iido iiadverse iidrug iireactions iioccur? ii- iiAnswers ii-Example: iia iireceptor
iiis iiactivated iiin iia iiblood iivessel iiby iia iidrug iidesigned iito iitreat iihypertension. iiThe
iirector iiis iiactivated iiby iithe iiligand iithat iiis iibound iito iiit, iiand iithe iiblood iipressure iiis
iilowered. iiHowever, iithis iireceptor iimay iilocated iiin iiother iiareas iiof iithe iibody. iiThe
iisubsequent iiactivation iiof iithis iireceptor iiin iiother iiareas iiof iithe iibody iiis iian iiexample iiof
iian iiadverse iieffect.
Adverse iieffects ii- iiAnswers ii-1. iiExtension iiof iitherapeutic iieffect
, 2. iiUnrelated iito iimain iidrug iiaction
3. iiAllergic iireaction
4. iiDependence iiand iiaddiction
5. iiTeratogenesis
6. iiAdverse iibiotransformation iireactions
Why iidoes iidrug iivariability iiexist ii- iiAnswers ii-1. iiGenetic iiFactors
2. iiEnvironmental iifactors
3. iiDiseased iistates ii(cardiovascular iior iikidney iidisease iifor iiexample)
4. iiAltered iiPhysiological iistate
-pregnant iior iielderly
5. iiOther iidrugs iipresent ii(competition)
The iiprocess iiof iideveloping iia iinew iidrug ii- iiAnswers ii-1. iiPre-clinical iitesting
-safety iiand iipotential iiefficacy iiin iilab iianimals
2. iiPhase iiI iiClinical iiTrial
-safety iiand iitolerability iiin iihealthy iivolunteers
3. iiPhase iiII ii
-effectiveness iiand iisafety iiin iia iismall iinumber iiof iipatients
4. iiPhase iiIII
-effectiveness iiand iisafety iiin iia iilarge iinumber iiof iipatients
5. iiPhase iiIV
-post iimarket iisurveillance iifor iiadverse iieffects iiand iisafety
How iido iidrugs iirestore/modify iithe iinormal iifunction iiof iithe iinervous iisystem? ii-
iiAnswers ii-Drugs iican iirestore iithe iinormal iifunction iiof iithe iinervous iisystem iithrough
iire-uptake iiof iineurotransmitters iiby iipost-synaptic iineurons. iiAn iiexample iiof iithis iiwould
iibe iitaking iian iiSSRI iifor iidepression.
Drugs iican iialso iimodify iithe iifunction iiof iithe iinervous iisystem iithrough iidisturbing iithe
iinatural iiconcentrations iiof iineurotransmitters iithrough iiillicit iiand/or iiprescribed iidrug
iiuse. iiAn iiexample iiof iithis iiwould iibe iitaking iia iinarcotic iianalgesic iisuch iias iimorphine
iito iirelieve iipost-op iipain.
What iiproperties iiof iia iisubstance iicontribute iito iiabuse iiand iidependence? ii- iiAnswers ii-
1. iiTolerance
2. iiWithdrawal
3. iiLoss iiof iicontrol ii(compulsion)
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller millyphilip. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $12.49. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
75632 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now