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Clinical Pharmacology Exam Questions And Answers With Verified Solutions Latest Update 2024/2025.
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Clinical Pharmacology Exam Questions And Answers With Verified Solutions Latest Update 2024/2025.
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Clinical Pharmacology Exam Questions And AnswersWith Verified Solutions Latest Update 2024/2025.
What is the MC pathogen of folliculitis? - ANSWER Staphylococcus Aureus
What is the TOC for folliculitis? - ANSWER Mupirocin (Bactroban) Ointment
Covers MRSA
* Do not share razors.
What is the pathogen of Hot Tub folliculitis? - ANSWER Pseudomonas aeruginosa
Pt J is on daily NSAID therapy for OA. She presents to your office c/o epigastric pain for 4 weeks. It
increases with meals and subsides after a few hours. After your PE you suspect NSAID gastritis. What is
the TOC? - ANSWER PPI = Omeprazole
Take 30 min - 1 hour before a meal
** Allow 4 months before before trying a different PPI treatment.
* Risk of fracture with LT use, usually d/c after 8-12 weeks.
What is the TOC for mild gastritis and GERD? - ANSWER Lifestyle changes!
Weight loss, decrease caffeine, minimize fatty/fried and spicy foods.
Increase HOB when sleeping, and do not eat within 2 hours of sleeping.
When is endoscopy indicated with GERD or gastritis? When is a rectal exam necessary? - ANSWER
UGI or colonoscopy with alarm sx = sever pain, weight loss, vomiting, GI bleeding, anemia, etc)
Rectal exam always.
What is the MOA with PPI's? - ANSWER Suppresses gastric acid secretion by inhibition of the
H+/K+ ATPase enzyme system.
A swab culture and stain from uretheral discharge shows gram negative diplococci. How do you treat? -
ANSWER Ceftriaxone = TOC
Cefixime = secondary
If disseminated (arthralgias, rash, tenosynovitis) then IV ceftriaxome + cefixime po.
A joint aspiration shows negative birefringent crystals. How do you treat gout in an exacerbation? In
between? - ANSWER Active = Indomethacin [NSAID]
In between = Allopurinol, colcichine, probenecid, febuxostat
What gout treatments are specific for overproducers? Undersecreters? - ANSWER
Overproducers = Probenecid, Sulfinpyrazone [uricosuric]
, Undersecreters = Allopurinol, Febuxostat [xanthine oxidase inhibitors]
Pt L presents with a unilateral headache, 7/10 behind the right eye, that lasts for 20 minutes several
times a day. He also has right sided tearing and rhinorrhea. How do you treat? - ANSWER 1st =
100% O2 for 15 minutes
2nd = Triptans (Sumatriptan or Zolmitriptan nasally)
What are some AE of triptans? What should you avoid while on them? - ANSWER Rebound HA,
nausea
Avoid smoking, alcohol, and taking within 24 hours of an erogot alkaloid [dihydroergotamine]
T or F: Allopurinol and febuxostat are okay to use together. - ANSWER False, they have the same
MOA/indication so both together is just too much.
What is the TOC for a tension HA? - ANSWER Analgesics = Ibuprofen, Excedrin
Migrane overlap = ergotamine
BOTH = Lifestyle changes of regular sleep, decreased caffeine, relaxation
Pt F, a 28 yo post pregnancy female, present to the office with anal itching and BRBPR. PE reveals
hemorrhoids. How do you treat? - ANSWER 1) High fiber diet with fluid, exercise and sitz baths
2) Rubberband ligation
3) Hemorrhoidectomy
Alternative = Witch Hazel for prutitis
Lidocaine and praoxime and phenylephrine and dibucaine and hydrocortisone
** Preparation H and Tucks comes in many mixes of drugs for pain, anti-pruritic (steroids and witch
hazel), and lubrication.
What is the TOC for genital herpes (1 or 2)? - ANSWER VALCYCLOVIR + acetaminophen for pain
Famcyclovir and acyclovir are secondary.
Can intermittent therapy with antivirals be used to decrease intensity and duration of outbreaks? -
ANSWER Yes, pt can take them for 2-5 days when an outbreak begins.
If episodes are >6 per year, then consider suppressive therapy = antiviral once daily.
A patient presents with the classic Shingles sx. How do you treat? - ANSWER Acyclovir = TOC
and NSAIDs for pain.
What is a secondary treatment for Shingles, used with postherpetic neuralgia? - ANSWER
Gabapentin and Lidocaine patches with postherpetic neuralgia.
Capsacian cream (Zosterix) can also be used, but it is neurotoxic.
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