Inflammation and phases of healing
[4 Phases of Healing:]
,During which stage:
Tissue healing and repair process happen? Tissue matrix created, repair cells,
fibroblasts, myofibroblasts, endothelial cells, etc. - Answer- Proliferation (repair) &
Migration
Inflammation and phases of healing
[4 Phases of Healing:]
Proliferation & Migration: What are the 4 Components of Matrix: "FPEC" - Answer-
Fibronectin (Scallfold),
Proteoglycans (PGs),
Elastin
Collagen.
Inflammation and phases of healing
[4 Phases of Healing:]
The bodies vascular reaction to cell injury to avoid blood loss. Coagulation starts with a
fibrin clot, platelets release chemokines that attract inflammation cells for growth; Mast
cells release Histamine - Answer- Hemostasis
With Neoplasia as PTs, we have to be cautious with what 2 deep modalities? - Answer-
friction massage
heat
Inflammation and phases of healing
[4 Phases of Healing:]
What happens during the Angiogenesis & Neovascularization phases - Answer- Growth
of new blood vessels and increase granulation tissue is formed
Inflammation and phases of healing
[4 Phases of Healing:]
During this phase, tissue repairs to restore to optimal function. - Answer- Remodeling &
Maturation (repair/scar)
Inflammation and phases of healing
[4 Phases of Healing:]
Remodeling & Maturation
What types of tissue:
-Don't regenerate (3)
-Do Regenerate (3)
Cell proteins altered/denatured; Loss of nucleus but cell shape and organ structures are
preserved by necrotic tissue that remains firm.
An example would be during an MI (sudden stoppage of blood) - Answer- Coagulative
necrosis
[Types of Necrosis]
Takes place in the following ways; brain infarct (stroke), bacterial infections
(abscesses); wet gangrene where soft tissues becomes filled with fluid; tissue
architecture is lost - Answer- Liquefactive Necrosis
[Types of Necrosis]
A combination of coagulative and liquefactive necrosis (i.e., Tuberculosis) - Answer-
caseous necrosis
[Types of Necrosis]
What type of necrosis occurs when fatty tissue is broken down into fatty acids such as
in the areas of the Breast, pancreas, and other abdominal organs
(Action of Lipases) - Answer- Fat Necrosis
[Type of Necrosis]
What type of necrosis results in death of tissue from hypoxia, commonly from
arteiosclerosis and affecting lower leg; may be be classified as dry, where the skin
appears brown and wrinkled, or wet, where the skin appears cold, swollen and black as
a result of liquefactive necrosis occurring at the site? - Answer- Gangrenous Necrosis
[Types of Necrosis]
What type of necrosis is blood vessel
death of a cell is replaced by fiber such as that with necrosis of immune reactions
(immune vasculitis/endocarditis) - Answer- Fibrinoid Necrosis
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