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NRNP 6550 Final Exam Review Questions And All Correct Answers.
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Addison's Disease - Answer - Primary adrenal insufficiency is dysfunction of adrenal cortices. - Secondary adrenal insufficiency is result of insufficient ACTH. S&S: weakness, fatigue, HA, nausea, hyperpigmented skin (lack of cortisol), sparse axillary hair, abd pain. Diagnose: Abd CT, h...

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  • November 12, 2024
  • 3
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • dysfunction of adrenal cortices

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  • NRNP 6550
  • NRNP 6550

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NRNP 6550 Final Exam Review
Questions And All Correct Answers.
Addison's Disease - Answer - Primary adrenal insufficiency is dysfunction of adrenal cortices.

- Secondary adrenal insufficiency is result of insufficient ACTH.



S&S: weakness, fatigue, HA, nausea, hyperpigmented skin (lack of cortisol), sparse axillary hair, abd pain.



Diagnose: Abd CT, head CT, Cortrosyn ACTH stim test, pan culture.



Findings: low Na, hyperK, low glucose, elevated ESR, neutropenia, esosiniphilia, lymphocytosis, hyperCal,
low plasma cortisol, elevated BUN, metabolic acidosis.



Treat: NS or D5NS, IV hydrocortisone, electrolyte replacement, monitor for decomp., IV abx if indicated.



Cushing's Syndrome - Answer - Hypercortisolemia (iatrogenic from glucocorticoid use, pituitary tumors,
and ectopic ACTH-secretion from tumors outside of the pituitary).



S&S: round face, obesity/weight gain, hirsutism, HTN, lethargy, menstrual changes, abnormal glucose
tolerance, decreased libido, striae, acne, EKG abnormalities, osteopenia, female balding.



Diagnose: ask about steroid-use, 24-hour urine free cortisol test, overnight DST test, and late-night
salivary cortisol test.



Cushing's Tests - Answer 24-hour urine:

- measures cortisol secretion that is not bound to cortisol-binding globulin.

- needs to be done at least twice.

-Assay levels between 3.5 and 45 are NORMAL



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