DX RA? - answer✔arthrocentesis for synovial fluid analysis, ANA negative to rule out SLE, Rheumatoid
factor, Anti-CCP antibodies
1st line treatment for RA? - answer✔Methotrexate- DMARD; myelosuppression and hepatic fibrosis SE;
CI in child-bearing women
Non-biologic DMARDS continued through perioperative period? - answer✔Methotrexate, Leflunomide,
Hydroxychloroquine, and Sulfasalazine
Dx of Giant cell arteritis (vasculitis - answer✔temporal artery biopsy; MRA of CTA if unable to do biopsy,
elevated CRP >10
highly specific for Temporal Arteritis? - answer✔jaw claudication
tx of giant cell arteritis - answer✔high dose corticosteroids (prednisone), aspirin to decrease risk of
vision loss or CVA
? binds to CD4 receptor and co-receptor CCR5 or CXCR4? - answer✔gp 120 = HIV protein
most common, most aggressive and world wide HIV? - answer✔HIV-1
AIDs? - answer✔CD4 <200 &/OR AIDs defining illness
can be detected in blood in 10 days after infection? - answer✔P24 antigen- NOT a standalone test
serum testing, EIA and Western Blot? - answer✔3rd generation immunoassasy for HIV antibody testing
@12 weeks post infection
better for acute HIV infection detection? - answer✔4th generation antigen/antibody test; if positive,
differentiation HIV1 or 2 immunoassay should be completed
viral load? - answer✔perform to clarify Dx in negative or indeterminate differentiation immunoassasy
and Tx monitoring
goal of viral load? - answer✔every 3 months on tx for viral suppression monitoring; <50
test to determine which drug to avoid with viral load >500? - answer✔Resistant Testing for HIV
treatment
test hypersensitivity to Abacavir, 100% sensitivity? - answer✔HLA-B*5701 Screening
test when initiating CCR5 inhibitor or failure with CCR5 inhibitors> - answer✔Co-receptor Tropism Assay
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