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HSC 4504 FINAL EXAM PRACTICE QUESTIONS AND ANSWERS
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HSC 4504 FINAL EXAM PRACTICE QUESTIONS AND ANSWERS A fibrotic mass of macrophages that surrounds & walls off the source of inflammation is known as a _____________. - ANSWER-granuloma Which property of the adaptive immune system enables it to respond to a large variety of antigens? - ANSWER-di...

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  • November 11, 2024
  • 58
  • 2024/2025
  • Exam (elaborations)
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  • hsc 4504 final exam practice questions and answers

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HSC 4504 FINAL EXAM PRACTICE

QUESTIONS AND ANSWERS


A fibrotic mass of macrophages that surrounds & walls off the source of inflammation is known as a

_____________. - ANSWER✔✔-granuloma


Which property of the adaptive immune system enables it to respond to a large variety of antigens? -

ANSWER✔✔-diversity


The type of immune response mediated by naive lymphocytes that occurs on first exposure to antigen is

called: - ANSWER✔✔-primary


Activated T lymphocytes preferentially migrate to - ANSWER✔✔-inflamed tissues


Immunity mediated by antibodies is known as - ANSWER✔✔-humoral immunity


Which property of the adaptive immune system leads to rapid and enhanced responses to repeat

exposures to the same antigens? - ANSWER✔✔-memory


Cellular messengers that mediate immune responses are known as: - ANSWER✔✔-cytokines


The name of the organ that raises the body's temperature when stimulated by endogenous pyrogens

released by white blood cells is the: - ANSWER✔✔-hypothalamus


Lymphocytes are the only cells with clonally distributed receptors with fine specificities for different

antigens. - ANSWER✔✔-True


Acquired immunity is both antibody and cell-mediated. - ANSWER✔✔-True

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Which property of the adaptive immune system ensures that distinct antigens elicit responses that target

those antigens? - ANSWER✔✔-specificity


Which of the following is NOT a type of immune effector cell? - ANSWER✔✔-erythrocyte


Which of the following is NOT a type of antigen presenting cell? - ANSWER✔✔-red cell


An overactive immune response to harmless antigens is called - ANSWER✔✔-hypersensitivity


The innate cell type important in first line of defense against microbes is the: - ANSWER✔✔-neutrophil


Which type of host defense mediates initial protection against infections and is always present in healthy

individuals? - ANSWER✔✔-innate immunity


Antigen presenting cells capture antigens of microbes that enter through epithelia, concentrate these

antigens in lymphoid organs, and display the antigens for recognition by T cells. - ANSWER✔✔-True


Lymphadema occurs when lymphatic fluid accumulates in the soft tissues, especially arms and legs. -

ANSWER✔✔-true


Monocytes can differentiate into which cell type? - ANSWER✔✔-dendritic cells


In the Lymph nodes, paracortex contains - ANSWER✔✔-Tcells and antigen presenting cells


Lymph node filter lymph of the pathogens and other debris and return the fluid back to the circulatory

system. - ANSWER✔✔-True


Which of the following is not derived from a myeloid progenitor cell? - ANSWER✔✔-NK cell


What is TRUE about macrophages? - ANSWER✔✔-They kill intracellular pathogens




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These cells of the immune system are recruited from the circulation to sites of infection and tissue

damage during inflammation - ANSWER✔✔-Phagocytes


Which cell is most important for the defense against parasitic organisms ? - ANSWER✔✔-Eosinophils


Which primary lymphoid organ generates all circulating blood cells in an adult as well as it is a site for B

cell maturation - ANSWER✔✔-Bone marrow


Which of the following cell plays a role in allergic reactions ? - ANSWER✔✔-Basophils


Which of the following cells is not an antigen presenting cell ? - ANSWER✔✔-T-cells


Which progenitor is most often associated with adaptive immunity? - ANSWER✔✔-Lymphoid

progenitors


The two principal phagocytes are: - ANSWER✔✔-Neutrophils and monocytes


What is NOT a function of the lymphatic system? - ANSWER✔✔-Maintain the blood pressure and

maintain homeostasis


Mucosa Associated Lymphoid Tissue (MALT) is an encapsulated tissue in mucosa of respiratory,

gastrointestinal & genitourinary tract and makes up > 50% of the lymphoid tissue. - ANSWER✔✔-False


The ________ is the largest secondary lymphoid organ and filters blood to remove antigens. -

ANSWER✔✔-spleen


Which of the following lymphoid cells do not specifically recognize antigen? - ANSWER✔✔-Natural Killer

Cells


The adaptive immune function of the spleen is found in the _______________. - ANSWER✔✔-White

pulp

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Choose the correct statement about T- cells - ANSWER✔✔-specifically recognize Ag (via the TcR)


Which of the following is not a component of innate immunity? - ANSWER✔✔-Antibodies


Which of the following organs is responsible for maturation of T cells? - ANSWER✔✔-thymus


I am a circulating cell involved in IgE type allergic reactions. I am a mediator of allergic reactions because

I can release granules that contain heparin and histamines. I am a: - ANSWER✔✔-Basophil


I am a professional at finding antigens and have a very long reach. I frequently interact with T cells

(shown in green in pic) in antigen presentations. I am a: - ANSWER✔✔-dendritic cell


MALT organs include: - ANSWER✔✔-All of the above


Antigen presentation and immune responses do not occur in the primary lymphoid organs. -

ANSWER✔✔-True


Primary lymphoid organs include: - ANSWER✔✔-C and D


I non-specifically recognize altered MHC proteins on the surface of virally infected or "corrupted" cancer

cells. I then release toxic molecules to kill the altered cell (in the picture I am killing a cancer cell) . I am a:

- ANSWER✔✔-natural killer cell


Which of the following statements about mast cells is FALSE? - ANSWER✔✔-Important defense against

parasitic infections


Which of the following is NOT a characteristic of macrophages? - ANSWER✔✔-Dampen allergic and

inflammatory responses


True or False: Inflammation is the body's specific response to antibodies or physical damage. -

ANSWER✔✔-False

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