ABX
examples of 2nd gen cephalosporins - ✔️✔️cefaclor
cefuroxime
cefoxitin
cefoteten
examples of carbapenems - ✔️✔️imipenem/cilastatin
meropenem
doripenem
ertapenem
4 classes of B Lactams - ✔️✔️penicillins
cephalosporins
monobactams
carbapenems
MOA of B lactams - ✔️✔️inhibit cell wall synthesis
4 subclasses of penicillins - ✔️✔️natural
AminoPCN
PCNase resistant
anti-pseudomonal
are penicillins time or concentration dependent - ✔️✔️time
examples of natural pcn - ✔️✔️pcn G
pcn V
examples of AminoPCN - ✔️✔️ampicillin
amoxicillin
examples of PCNase resistant - ✔️✔️naficillin
oxacillin
dicloxacillin
examples of anti-pseudomonal - ✔️✔️piperacillin
tircarcillin
coverage of natural PCN - ✔️✔️mainly gram +
few gram -
coverage of AminoPCN - ✔️✔️gram + and -
, coverage of PCNase resistant - ✔️✔️gram +
coverage of anti-pseudomonal - ✔️✔️gram -
PCNase R or S -- natural - ✔️✔️Sens
PCNase R or S -- AminoPCN - ✔️✔️Sens
PCNase R or S -- PCNase resistant - ✔️✔️Resistant
PCNase R or S -- anti-pseudomonal - ✔️✔️Sens
DOC for syphillis - ✔️✔️natural PCN
what shape is syphillis - ✔️✔️spirochete
DOC for otitis media - ✔️✔️amoxicillin
DOC for strep pharyngitis - ✔️✔️amoxicillin
DOC for endocarditis prophylaxis - ✔️✔️amoxicillin
DOC for mastitis - ✔️✔️dicloxacillin
main use of anti-pseudomonal pcns - ✔️✔️severe infection or pseudomonas
how are PCN eliminated from the body - ✔️✔️renal
EXCEPT "NO" -- nafcillin and oxacillin which are hepatic
MC adverse effect of PCN - ✔️✔️GI distress (n/v/d)
are PCN bacteriostatic or bactericidal - ✔️✔️bactericidal
what do bacteria produce to combat beta lactams - ✔️✔️beta lactamase
examples of 1st gen cephalosporin - ✔️✔️cefazolin
cephalexin
examples of 3rd gen cephalosporin - ✔️✔️cefdinir
ceftriaxone
examples of 4th gen cephalosporin - ✔️✔️cefepime
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