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Exam (elaborations)

NR 507 midterm Test Questions and Answers

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  • Course
  • NR 507 ADVANCED PATHOPHYSIOLOGY
  • Institution
  • NR 507 ADVANCED PATHOPHYSIOLOGY

NR 507 midterm Test Questions and Answers

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  • November 9, 2024
  • 23
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NR 507 ADVANCED PATHOPHYSIOLOGY
  • NR 507 ADVANCED PATHOPHYSIOLOGY
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Zanaya
NR 507 midterm




Hives (urticaria) are an example of a: - Answer-Type 1 hypersensitivity reaction.



Anaphylaxis is what type of reaction? - Answer-type 1 hypersensitivity



Which of the following are considered the "first responders" of the innate immune system? - Answer-
neutrophils



Allergic contact dermatitis is an example of what type of

hypersensitivity reaction. - Answer-type 4 hypersensitivity reaction



Type 2 (Cytotoxic) hypersensitivity reactions are mediated by: - Answer-IgG or IgM



Type 1 hypersensitivity reaction is mediated by - Answer-IgE



Allergic asthma is an example of - Answer-type 1 hypersensitivity reaction



type 2 hypersensitivity - Answer-tissue specific

,Primary effector cells of type 2 - Answer-macrophages



Examples of type 2 reactions - Answer-drug allergies, hemolytic anemia, blood transfusion mismatch,
allergies against infectious agents



Type 2 causes - Answer-The cell to be destroyed by the antibody

Cell destruction through phagocytosis by macrophages

Damage to the cell by neutrophils triggering phagocytosis

Natural killer cells to release toxic substances that destroy the target cell

Malfunction of the cell without destruction



Type 3 hypersensitivity reaction - Answer-antigen-antibody response



Where does the antibody bind to the antigen in type 3 response? - Answer-in blood or body fluids and
then circulates to tissue



Where does the antibody bind to the antigen in type 1, 2, and 4? - Answer-on cell surface



Primary effector cell in type 3 - Answer-neutrophils



example of type 3 reaction - Answer-serum sickness



type 4 hypersensitivity reaction - Answer-cell-mediated response



primary mediators of type 4 - Answer-lymphocytes and macrophages

, type 4 mediated by - Answer-T lymphocytes and do not use antibodies



example of type 4 - Answer-localized contact dermatitis (poison ivy)



Damage occurs with ABO incompatibility because: - Answer-Complement damages RBC membrane
causing cell lysis.



Which of the following is the underlying pathology for hay fever? - Answer-mast cell degranulation



The diagnosis for an individual who presents to the office with sudden swollen lips and eyes, shortness
of breath and throat tightness after a bee sting is: - Answer-anaphylaxis



Which of the following assessment findings would be expected in a patient who presents with urticaria?
- Answer-Eosinophilia.



An example of a primary immunodeficiency is: - Answer-Chronic Granulomatous Disease.



what is a predominant cause of secondary immune deficiencies worldwide. - Answer-Malnutrition



Which of the following is an autoimmune disease? - Answer-Systemic Lupus Erythematosus (SLE).



Which is true about a primary immunodeficiency? - Answer-It is the result of a single gene defect.
(genetics)



Examples of secondary immunodeficiency - Answer-HIV, cancer

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