3. Mirtazapine is an antagonist at which receptor? - ANSWER ALPHA-2-
ADRENERGIC
4. The risk of increased psychosis for pts with psychotic disorders who take
bupropion is attributable to enhancement of: - ANSWER DOPAMINE
5. Which dietary supplement has demonstrated some efficacy in Tx of
depression? - ANSWER S-ADENOSYL-L-METHIONINE (SAME)
6. The side effects of sedation and weight gain are associated with
mirtazepine's antagonism of which of the following receptors? - ANSWER
H1
,7. Pt taking venlafaxine for months stops abruptly and calls psychiatrist 3 days
later with nausea, insomnia, muscle aches, anxiety, dizziness, and transient
"electric shock" sensations. The most likely cause: - ANSWER
ANTIDEPRESSANT WITHDRAWAL
8. 58 y/o pt is started on citalopram 20mg for MDD. After 3 wks pt reports
some improvement in vegetative sxs but remains dysphoric. What is the
next step? - ANSWER CONTINUE CITALOPRAM AT THE PRESENT DOSE
WITH NO ADDITIONAL MED
10.An effective antidepressant for depression w/ atypical features is: -
ANSWER PHENELZINE
11.Why is l-methylfolate preferable to folate in adjunctive tx of depression? -
ANSWER INCREASE TRANSFER ACROSS BBB
12.Phenylethylamine antidepressant that targets serotonin and
norepinephrine reuptake inhibition: - ANSWER VENLAFAXINE
13.Pt presents to ED with 5-day hx of N/V, diarrhea, HR of 90, BP 150/92, and
temp 100, sweating, tremor, hyperreflexia and distractibility, normal labs
an and CT head, and years of Fluoxetine use. One week ago a new med was
started, what med was it?: - ANSWER TRAMADOL
, 14.19 y/o pt presents for evaluation of depression. Pt reports a generally very
low mood, although it brightens up briefly when something good happens.
Pt reports feeling best in the morning. Pt has been sleeping and eating
more than usual, and complains of feelings of heaviness in the extremities.
Pt reports always being very sensitive to perceived rejection by others.
Trials with two selective serotonin reuptake inhibitors (SSRIs) have failed.
Which of the following treatments may be particularly effective for this pt?
- ANSWER TRANYLCYPROMINE
15.Which of the following meds has the lowest likelihood of discontinuation
symptoms if the medication is abruptly stopped? - ANSWER
FLUOXETINE
16.What med has some evidence of effectiveness in both
psychotic/nonpsychotic subtypes of body dysmorphic disorder? - ANSWER
FLUOXETINE
17.What med is most potent inhibitor of the norepinephrine transporter? -
ANSWER PAROXETINE
18.What pharmacological treatment should be used for long-term insomnia in
pts with dementia over 65 years of age? - ANSWER TRAZODONE
19.Mirtazepine (vs other antidepressants) has low incidence of what side
effect? - ANSWER SEXUAL SIDE EFFECTS
20.Orthostatic hypotension is least likely to occur as a S/E with what
antidepressants? - ANSWER SERTRALINE, NORTRIPTYLINE,
IMIPRAMINE, AMITRIPTYLINE, TRAZODONE
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