Pharmacotherapeutics for Advanced Practice- A Practical Approach 5th Edition Arcangelo Test Bank LATEST
Pharmacotherapeutics for Advanced Practice- A Practical Approach 5th Edition Arcangelo Test Bank LATEST
Pharmacotherapeutics for Advanced Practice- A Practical Approach 5th Edition Arcangelo Te...
A. The National Council of State Boards of Nursing
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B. The U.S. Drug Enforcement Administration
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C. The State Board of Nursing
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D. The State Board of Medical Examiners
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ANS: n j D PTS: n j 1
3. Clinical judgment in prescribing includes:
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A. Factoring in the cost to the patient of the medication prescribed
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B. Always prescribing the newest medication available for the disease process
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C. Handing out drug samples to poor patients nj nj nj nj nj nj
D. Prescribing all generic medications to cut costs nj nj nj nj nj nj
ANS: n j A PTS: n j 1
4. Criteria for choosing an effective drug for a disorder include:
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A. Asking the patient what drug they think would work best for them
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B. Consulting nationally recognized guidelines for disease managementnj nj nj nj nj nj
C. Prescribing medications that are available as samples before writing a prescription
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D. Following U.S. Drug Enforcement Administration (DEA) guidelines
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nj forprescribing
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ANS: n j B PTS: n j 1
5. Nurse practitioner practice may thrive under health-care reform due to:
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A. The demonstrated ability of nurse practitioners to control costs and improve
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nj patientoutcomes nj
B. The fact that nurse practitioners will be able to practice independently
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C. The fact that nurse practitioners will have full reimbursement under health-
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carereform nj
D. The ability to shift accountability for Medicaid to the state level
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ANS: n j A PTS: n j 1
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Chapter 2.Pharmacokinetic Basis of Therapeutics and Pharmacodynamic
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MULTIPLE CHOICE nj
1. A patient's nutritional intake and lab work reflects hypoalbuminemia. This is critical
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toprescribing because:
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A. Distribution of drugs to target tissue may be affected nj nj nj nj nj nj nj nj
B. The solubility of the drug will not match the site of absorption
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C. There will be less free drug available to generate an effect
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D. Drugs bound to albumin are readily excreted by the kidney
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ANS: n j A PTS: n j 1
2. Drugs that have a significant first-pass effect:
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A. Must be given by the enteral (oral) route only
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B. Bypass the hepatic circulation nj nj nj
C. Are rapidly metabolized by the liver and may have little if any desired action
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D. Are converted by the liver to more active and fat-soluble forms
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ANS: n j C PTS: n j 1
3. The route of excretion of a volatile drug will likely be:
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A. The kidneys nj
B. The lungs nj
C. The bile and feces nj nj nj
D. The skin nj
ANS: n j B PTS: n j 1
4. Medroxyprogesterone (Depo Provera) is prescribed IM to create a storage reservoir of nj nj nj nj nj nj nj nj nj nj nj
thedrug. Storage reservoirs:
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A. Assure that the drug will reach its intended target tissue
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B. Are the reason for giving loading doses
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C. Increase the length of time a drug is available and active nj nj nj nj nj nj nj nj nj nj
D. Are most common in collagen tissues
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ANS: n j C PTS: n j 1
5. The NP chooses to give cephalexin every 8 hours based on knowledge of the drug's:
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A. Propensity to go to the target receptor nj nj nj nj nj nj
B. Biological half-life nj
C. Pharmacodynamics
D. Safety and side effects nj nj nj
ANS: n j B PTS: n j 1
6. Azithromycin dosing requires the first day's dose be twice those of the other 4 days of
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theprescription. This is considered a loading dose. A loading dose:
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A. Rapidly achieves drug levels in the therapeutic range nj nj nj nj nj nj nj
B. Requires four to five half-lives to attain nj nj nj nj nj nj
C. Is influenced by renal function
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D. Is directly related to the drug circulating to the target tissues
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ANS: n j A PTS: nj nj n j 1
7. The point in time on the drug concentration curve that indicates the first sign of a
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therapeuticeffect is the:
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A. Minimum adverse effect level nj nj nj
B. Peak of action nj nj
C. Onset of action nj nj
D. Therapeutic range nj
ANS: n j C PTS: n j 1
8. Phenytoin requires a trough level be drawn. Peak and trough levels are done:
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A. When the drug has a wide therapeutic range nj nj nj nj nj nj nj
B. When the drug will be administered for a short time only
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C. When there is a high correlation between the dose and saturation of receptor sites
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D. To determine if a drug is in the therapeutic range
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ANS: n j D PTS: n j 1
9. A laboratory result indicates the peak level for a drug is above the minimum
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toxicconcentration. This means that the:
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A. Concentration will produce therapeutic effects nj nj nj nj
B. Concentration will produce an adverse response nj nj nj nj nj
C. Time between doses must be shortened nj nj nj nj nj
D. Duration of action of the drug is too long nj nj nj nj nj nj nj nj
ANS: n j B PTS: n j 1
10. Drugs that are receptor agonists may demonstrate what property?
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A. Irreversible binding to the drug receptor site nj nj nj nj nj nj
B. Up-regulation with chronic use nj nj nj
C. Desensitization or down-regulation with continuous use nj nj nj nj nj
D. Inverse relationship between drug concentration and drug action
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ANS: n j C PTS: n j 1
11. Drugs that are receptor antagonists, such as beta blockers, may cause:
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A. Down-regulation of the drug receptor nj nj nj nj
B. An exaggerated response if abruptly discontinued
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C. Partial blockade of the effects of agonist drugs nj nj nj nj nj nj nj
D. An exaggerated response to competitive drug agonists
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ANS: n j B PTS: n j 1
12. Factors that affect gastric drug absorption include:
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A. Liver enzyme activity nj nj
B. Protein-binding properties of the drug molecule nj nj nj nj nj
C. Lipid solubility of the drug nj nj nj nj
D. Ability to chew and swallow nj nj nj nj
ANS: n j C PTS: n j 1
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