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NUR 239 Exam 1 With 100% Verified Solutions | Updated & Verified | 2024
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NUR 239 Exam 1 With 100% Verified Solutions | Updated & Verified | 2024
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NUR 239 Exam 1 With 100% VerifiedSolutions | Updated & Verified | 2024
what variable relate to pharmacokinetics? - ✔✔genetics, age, sex, renal function
pharmacokinetics process - ✔✔ADME
absorption, distribution, metabolism, excretion
in older adults, all processes are affected
Absorption - ✔✔the process or action by which one thing absorbs or is absorbed by
another. paceman
Distribution - ✔✔involves transport of drug molecules throughout the body. Albumin is binding protein
lightning mcqueen
, If there are low protein levels, there's a high chance of toxicity
Metabolism - ✔✔method of which drugs are inactivated or biotransformed in body. Takes place in liver
Wreck it Ralph
Excretion - ✔✔elimination of drug from body
Elsa
If renal function is decreased, there is a higher chance for toxicity
What happens if drugs bind with plasma proteins? - ✔✔Drug molecules bound to plasma proteins are
pharmacologically inactive because large size of complex prevents them from leaving bloodstream
through small openings in capillary walls and reaching their sites of action, metabolism, and excretion
Only free or unbound portion of drug acts on body cells
What factors affect absorption? - ✔✔dosage form
route of administration
Blood flow to site
GI F(x)
Presence of food or other drugs
What factors affect distribution of drug - ✔✔Rate and amount of blood flow
Solubility (protein binding)
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