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BMES 5024 Midterm Exam Study Guide Solutions

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BMES 5024 Midterm Exam Study Guide Solutions Andreas Vesalius () - ANSWER-First most accurate and comprehensive anatomical text "De Humani Corporis Fabrica" Seven Volumes on the structure of the human body William Harvey () - ANSWER-"On the Motion of the Heart and Blood in Animals" The first ...

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  • November 3, 2024
  • 27
  • 2024/2025
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KaylinHoffman
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BMES 5024 Midterm Exam Study Guide

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Andreas Vesalius (1514-1564) - ANSWER✔✔-First most accurate and comprehensive anatomical text

"De Humani Corporis Fabrica"


Seven Volumes on the structure of the human body


William Harvey (1578-1657) - ANSWER✔✔-"On the Motion of the Heart and Blood in Animals"


The first accurate theory of how the heart circulatory system operate.


Antonie van Leeuwenhoek (1632-1723) - ANSWER✔✔--Discovered bacteria, free-living and parasitic

microscopic protists, sperm cells, blood cells, microscopic nematodes....


-Opened up entire world of microscopic life


Edward Jenner (1749-1823) - ANSWER✔✔-Developed the first effective vaccine against smallpox


Crawford Williamson Long (1815-1878) - ANSWER✔✔-Pioneering physician who is credited with

discovering anesthesia. First surgical use of ether


William Rontgen (1845-1923) - ANSWER✔✔-Discovered X-rays


Received first Nobel Prize (1901)
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Ross Granville Harrison (1870-1959) - ANSWER✔✔-Discovered a method of tissue culture. Culture of frog

nerve tissue in blood clot


Nikolay Anichkov (1885-1964) - ANSWER✔✔-Discovered the role of cholesterol in coronary artery

disease


Alexander Fleming (1881-1955) - ANSWER✔✔-Discovered Penicillin. Novel prize in physiology and

medicine (1945)


Maurice Wilkins - ANSWER✔✔-Discovered the structure of DNA. Novel prize in physiology and medicine

(1962)


Model Systems - ANSWER✔✔--Basic cell biology & biochemistry


-Interactions between disease-causing agents & cells


-Drug effects on cells, aging process, nutritional studies, etc.


Toxicity Testing - ANSWER✔✔-Studies the effects of new drugs, cosmetics, and other chemicals on

survival and growth in variety of cell types.


Virology - ANSWER✔✔--Basic research on how viruses infect organisms


-clinical detection and isolation of viruses


Cell culture applications - ANSWER✔✔--genetic engineering


-gene therapy

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-drug screening & development


-cell based manufacturing


Primary cell cultures - ANSWER✔✔-primary neurons, HUVEC


-obtain directly from normal animal tissues


-limited life spam


-usually retain characteristics of in vivo cells in normal tissues


Continuous Cell Cultures - ANSWER✔✔-Transformed (immortalized) cell lines


BV-2, HMEC-1


-propagate indefinitely


-transformed using viral oncogenes or chemical treatments


-retain little of original in vivo characteristics


Cancer Cell Lines - ANSWER✔✔--continuous


-single cell type propagated in culture for limited number of divisions


-usually retain characteristics of in vivo cells in tumor tissues


-can grow longer than primary cell lines



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