PHAR 100 Final Exam Questions And Answers Rated A+ 2024.
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Course
PHAR 100
Institution
PHAR 100
PHAR 100 Final Exam Questions And Answers Rated A+ 2024.
Path of drug from when it enters to exits the body - correct answer. 1. Absorption
2. Distribution
3. Metabolism
4. Excretion
Absorption - correct answer. the movement of the drug from the site of administration i...
PHAR 100 Final Exam Questions And
Answers Rated A+ 2024.
Path of drug from when it enters to exits the body - correct answer. 1. Absorption
2. Distribution
3. Metabolism
4. Excretion
Absorption - correct answer. the movement of the drug from the site of
administration into the bloodstream
Distribution - correct answer. the movement of a drug from the blood to the site of
action and other tissues
Metabolism - correct answer. the conversion of a drug to a different chemical
compound.
Excretion - correct answer. moving of the drug and its metabolites out of the body
Routes of drug administration - correct answer. 1. Topical
- On the skin
-Transdermal
-Inhalation
2. Enteral
-Oral
-Suppository
-Buccal
3.Parenteral
-IV
-IM
-Subcutaneous
Why and how do adverse drug reactions occur? - correct answer. Example: a
receptor is activated in a blood vessel by a drug designed to treat hypertension. The
, rector is activated by the ligand that is bound to it, and the blood pressure is lowered.
However, this receptor may located in other areas of the body. The subsequent
activation of this receptor in other areas of the body is an example of an adverse effect.
Adverse effects - correct answer. 1. Extension of therapeutic effect
2. Unrelated to main drug action
3. Allergic reaction
4. Dependence and addiction
5. Teratogenesis
6. Adverse biotransformation reactions
Why does drug variability exist - correct answer. 1. Genetic Factors
2. Environmental factors
3. Diseased states (cardiovascular or kidney disease for example)
4. Altered Physiological state
-pregnant or elderly
5. Other drugs present (competition)
The process of developing a new drug - correct answer. 1. Pre-clinical testing
-safety and potential efficacy in lab animals
2. Phase I Clinical Trial
-safety and tolerability in healthy volunteers
3. Phase II
-effectiveness and safety in a small number of patients
4. Phase III
-effectiveness and safety in a large number of patients
5. Phase IV
-post market surveillance for adverse effects and safety
How do drugs restore/modify the normal function of the nervous system? - correct
answer. Drugs can restore the normal function of the nervous system through re-
uptake of neurotransmitters by post-synaptic neurons. An example of this would be
taking an SSRI for depression.
Drugs can also modify the function of the nervous system through disturbing the natural
concentrations of neurotransmitters through illicit and/or prescribed drug use. An
example of this would be taking a narcotic analgesic such as morphine to relieve post-
op pain.
What properties of a substance contribute to abuse and dependence? - correct answer.
1. Tolerance
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