33.1 33.1 AA BB CC DD EE Glomerulonephritis (Acute Poststreptococcal) > Quiz Results Quiz Results Your Score: 100 % Your Score: 100 % You answered 3 of 3 questions correctly. Question Question 1: 1: Correct Correct A 6-year-old boy presents with a new onset of oliguria and hematuria shortly a!e...
Your Score: 100 %
You answered 3 of 3 questions correctly.
Question 1: Correct
33.1
33.1 A 6-year-old boy presents with a new onset of oliguria and hematuria shortly a!er he has
recovered from an untreated sore throat. Additional workup finds hypertension, periorbital
edema, and impaired renal function with slightly increased amounts of protein in the urine.
A renal biopsy most likely would reveal electron-dense deposits in which of the following
sites?
AA Between the basement membrane and endothelial cells of the glomeruli
✓ BB Between the basement membrane and epithelial cells of the glomeruli
✓
CC Between the basement membrane and epithelial cells of the proximal tubules
DD Within the mesangium of the glomeruli
EE Within the juxtaglomerular apparatus
This study source was downloaded by 100000892566046 from CourseHero.com on 11-02-2024 16:04:18 GMT -05:00
Explanation:
B.
B. Acute di"use proliferative glomerulonephritis most commonly presents in children a!er a
group A β-hemolytic streptococcal infection; this explains the other name of this disorder:
acute poststreptococcal glomerulonephritis. Children develop signs of the nephritic syndrome
with hematuria, mild periorbital edema, and increased blood pressure. This disorder is
characterized by irregular larger subepithelial (between the basement membrane and
epithelial cells) electron-dense deposits.
67
67% of users answered correctly.
Source: Case Files: Pathology 2e
Question 2: Correct
33.2
33.2 Which of the following is the histologic hallmark for the diagnosis of rapidly progressive
glomerulonephritis?
✓ AA Crescents within the glomeruli
✓
BB Fibrinoid necrosis of the e"erent arterioles
CC Fibromuscular hyperplasia of the a"erent arterioles
DD "Spike and dome" appearance of the glomerular basement membrane
EE "Tram-track" splitting of the glomerular basement membrane
The correct answer is AA. You answered AA.
Explanation:
A.
A. Rapidly progressive glomerulonephritis is characterized histologically by the presence of
crescents within glomeruli (crescentic glomerulonephritis). A crescent, which is defined as
having at least three layers of cells between the visceral and parietal epithelium, is composed
of visceral and parietal epithelial cells, inflammatory cells, and fibrin. The three basic types of
RPGN, defined by the immune pathomechanism, are anti-GBM disease (linear immune
deposits), immune-complex–mediated disorders (granular immune deposits), and the pauci-
immune type (very few immune deposits).
67
67% of users answered correctly.
Source: Case Files: Pathology 2e
This study source was downloaded by 100000892566046 from CourseHero.com on 11-02-2024 16:04:18 GMT -05:00
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