Maximum amount of Sumatriptan that can be taken in 1 day - Correct Ans-200 mg
The ability of the anesthetic to penetrate the axon membrane is determined by what 3 properties? - Correct Ans-Lipid solubility, degree of ionization at tissue pH, molecular size
Why is epinephrine given with local ...
Pharmacology 5334 Module 3 Exam
Questions and Answers 2024
Maximum amount of Sumatriptan that can be taken in 1 day - Correct Ans-200 mg
The ability of the anesthetic to penetrate the axon membrane is determined by what 3
properties? - Correct Ans-Lipid solubility, degree of ionization at tissue pH, molecular
size
Why is epinephrine given with local anesthetics? - Correct Ans-Decreases local blood
flow; delays systemic absorption of the anesthetic; prolongs anesthesia; reduces the
risk of toxicity
Most widely used local anesthetic - Correct Ans-Lidocaine
What is a possible fatal reaction to benzocaine? - Correct Ans-Methemoglobinemia
What is included in application guidelines for topical anesthetics? - Correct Ans-Avoid
wrapping the site and heating the site; avoid application to open skin; use to smallest
amount to the smallest site
What is the best option for menstrual migraine? - Correct Ans-Low dose estrogen about
3 days prior to menses
What are the 3 main classes of opiod receptors? - Correct Ans-Mu, alpha, and delta
Which medication will reverse the effects caused by opioid agonists? - Correct Ans-
Naloxone (Narcan)
What medications are used to treat opioid induced constipation (OIC)? - Correct Ans-
Naloxegol, methylinaltrexone, and lubiprostone
Tolerance is defined as: - Correct Ans-increased doses of a medication needed to
obtain the same response
Physical dependence is defined as: - Correct Ans-abstinence syndrome with abrupt
discontinuation
Abuse is defined as: - Correct Ans-drug use that is inconsistent with medical or social
norms
Addiction is defined as: - Correct Ans-behavior pattern characterized by continued use
of a psychoactive substance despite physical, psychologic, or social harm
, What medication is used for opioid abuse? - Correct Ans-Naltrexone
Euphoria induced by morphine: - Correct Ans-an exaggerated sense of well-being
caused by the activation of mu receptors
What medication is given nasally for migraines? - Correct Ans-Butorphanol
Describe the mechanism of NSAIDs - Correct Ans-Inhibition of the cyclo-oxygenase
enzyme
Second generation Cox 2 inhibitors: - Correct Ans-suppress inflammation and cause
less risk for GI ulceration than Cox 1; increase the risk for heart disease
What medication should NOT be given with aspirin? - Correct Ans-Glucocorticoids
What medication is given for acetaminophen overdose? - Correct Ans-Acetylcysteine
What are non-endocrine therapeutic uses for glucocorticoids? - Correct Ans-RA, SLE,
IBS, bursitis, OA, gout, disorders of the eye
What is the danger of prolonged use of glucocorticoids? - Correct Ans-Adrenal
insufficiency
Methotrexate can cause fatal toxicities of: - Correct Ans-bone marrow, liver, kidneys,
lungs; hemorrhagic enteritis and GI perforation
What must be checked yearly while taking etanercept? - Correct Ans-TB
What is the mechanism of action of etanercept? - Correct Ans-Suppresses the immune
system
First line treatment of gout - Correct Ans-Indomethacin
When would you initiate a uricosuric medication? - Correct Ans-more than 3 gout
attacks per year
Non-opioid centrally acting analgesics - Correct Ans-Tramadol (suicide and seizure
risk), clonidine, Ziconotide, dexmetomidine (used for patients on mechanical ventilation)
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