MST Practice Exam Complete Questions With Well Defined Answers.
5 views 0 purchase
Course
MST
Institution
MST
Complete this sentence: A stringent test for_ __ is to inject cells into a host _ _ and examine their contribution to all tissues. - correct answer Pluripotency, blastocyst
Which of the following statements accurately describes the process of generating inter...
Complete this sentence: A stringent test for_ __ is to inject cells into a host _ _ and examine their
contribution to all tissues. - correct answer Pluripotency, blastocyst
Which of the following statements accurately describes the process of generating interspecies chimeras
to harvest human organs? - correct answer Genetic complementation is used where
the host species blastocyst cells are deficient in a key gene to make a particular organ and the donor
pluripotent cells provide the missing key gene in order to make a donor-specific organ.
Which of the following statements CORRECTLY describes a function of the Polycomb protein? - correct
answer Polycomb binds to trimethylated histone 3 lysine 27 (H3Me27) where it acts
to repress transcription of nearby genes
Which of the tests for stem cell pluripotency is considered the most stringent? - correct answer
Tetraploid complementation
Which of the following is one of the stem cell niches of the adult brain? - correct answer
Subventricular zone
Which of the following is not a change that takes place during early reprogramming of mouse fibroblast
cells to generate iPS cells? : - correct answer Endogenous expression of Oct 4
Culturing in "2i + LIF" medium: - correct answer enabled derivation of ES cells from
rats.
Which of the following is NOT a characteristic of the molecular profile of stem cells - correct answer
Have low levels of telomerase activity
Stemness' is a concept based on the notion that there are: - correct answer
molecular signals common to all stem cell types.
, Complete this sentence: In cancers, bivalent genes in stem cells are DNA methylated and the state of
genome-wide methylation as the tumour progresses is: - correct answer
Hypomethylated
Complete this sentence: Calico cats are - correct answer always female and the coat
colour is due to random inactivation of X-chromosomes.
During kidney development the nephrogenic niche comprises the uretetic tip and which other tissue? -
correct answer The cap mesenchyme
Wounding of a zebrafish heart by cryoinjury - correct answer results in de-
differentiation of cardiomyocytes that proliferate and re-differentiate.
During unidirectional stem cell division, - correct answer both daughter cells
become progenitor cells.
Complete this sentence taken from Scadden's (2006) definition of the stem cell niche. ' The niche saves
stem cells from depletion, while protecting the host from over-exuberant ____________' - correct
answer stem-cell proliferation
Which of the following statements about adult stem cells is correct? - correct answer
Homeostasis can be achieved via a balance of symmetrical divisions that produce either stem cells or
differentiated cells.
In conventional mouse ES cells derived from the inner cell mass, fibroblast growth factor (FGF) added to
the medium: - correct answer promotes differentiation
Which of the following is NOT part of the functional definition for stem cells? - correct answer
Express common transcripts
When comparing naïve and primed epiblast cells which of the following is NOT CORRECT? - correct
answer Both cell types undergo proliferation when treated with LIF
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller RealGrades. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $13.49. You're not tied to anything after your purchase.
