WGU D116 ADVANCED PHARMACOLOGY OA
FINAL EXAM 2024/2025 PRACTICE QUESTIONS
AND ANSWERS GRADED A+
What factor can be attributed to limited prescriptive authority for APRNs?
Inaccessibility of patient care
RATIONALE:Limiting prescriptive authority for APRNs can create barriers to
quality, affordable, and accessible patient care. It may also lead to poor
collaboration among providers and higher health care costs.
A patient reports that a medication prescribed for recurrent migraine headaches is
not working. Which action should be taken first?
Ask the patient about the number and frequency of tablets taken.
RATIONALE:using the drug as ordered. Asking the patient to tell the nurse how
many tablets are taken and how often helps the nurse determine compliance.
,WGU D116 ADVANCED PHARMACOLOGY
A patient is receiving intravenous gentamicin. A serum drug test reveals toxic
levels. The dosing is correct, and this medication has been tolerated by this patient
in the past. Which could be a probable cause of the test result?
The patient is taking another medication that binds to serum albumin
RATIONALE:Gentamicin binds to albumin, but only weakly, and in the presence
of another drug that binds to albumin, it can rise to toxic levels in blood serum.
The nurse is administering morning medications. The nurse gives a patient
multiple medications, two of which compete for plasma albumin receptor sites. As
a result of this concurrent administration, the nurse can anticipate that what might
occur? Select all that apply
Binding of one or both agents will be reduced, Plasma levels of free drug will rise,
The increase in free drug will intensify effects
RATIONALE:When two drugs bind to the same site on plasma albumin,
coadministration of those drugs produces competition for binding. As a result,
binding of one or both agents is reduced, causing plasma levels of free drug to
rise.The increase in free drug can intensify the effect, but it usually undergoes
rapid elimination. The increase in plasma levels of free drug is rarely sustained.
, WGU D116 ADVANCED PHARMACOLOGY
A patient asks a nurse why a friend who is taking the same drug responds
differently to that drug. The nurse knows that the most common variation in drug
response is due to differences in each patient's:
metabolism of drugs
RATIONALE:The most common source of genetic variation in drug response is
related to alterations in drug metabolism and is determined by genetic codes for
various drug-metabolizing isoenzymes.
A patient with migraines is started on a beta blocker. The nurse explains the
benefits of taking the medication for migraines. Which statement by the patient
indicates an understanding of the medication's effects?
“I need to take it every day to reduce the frequency of migraines.”
RATIONALE:When taken prophylactically, medications such as beta blockers can
reduce the frequency of migraine attacks. They do not provide complete relief from
migraines. They do not reduce the duration of migraines. They are not effective for
treating a migraine once the migraine has begun
A prescriber orders transdermal clonidine [Catapres TTS] for a patient with
hypertension. What will the nurse teach this patient?
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