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Maryville 660 Exam 2 Psycho-pharm Questions and Answers
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Maryville 660 Exam 2 Psycho-pharm Questions and Answers
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Maryville 660 Exam 2 Psycho-pharmQuestions and Answers
H1 blockade - Answer-sedation and weight gain
M1 blockade - Answer-anticholinergic side effects (dry mouth, blurred vision, urinary
retention, constipation)
Alpha 1 blockade - Answer-ortho hypotension, dizziness
VSSCs blockade - Answer-coma, seizures, card. arrhythmias, card. arrest, death, OD
RISK
Amitriptyline - Answer-can help w/ neuropathic type pain
Nortri - Answer-50-150mg. At least 12 hours post dose lab draw
TCA OD toxicity - Answer-wide QRS > 100ms - give bicarb and supportive care
Tertiary TCAs - Answer-blocks more serotonin than NE
secondary TCA - Answer-blocks more NE than Serotonin
Tertiary TCA (liver) - Answer-Liver makes more secondary and has a more
anticholinergic effect
SSRI/SNRI to MAOI - Answer-Depends on half life - wait 5 half lives (5-7 days) and start
MAOI - except prozac (wait 5 weeks!!)
MAOI to SSRI/SNRI - Answer-wait 2 weeks and then start
body needs to make more MAO
WASHOUT period
Who's your daddy - Answer-Suicide?
mood disorder?
psych hospitalizations?
anyone take Li or mood stabliizers, antidepress, antipsych?
ECT?
Who's your mama - Answer-Collateral Hx.
Hypothalamus - Answer-Sleep and appetite
PFC - Answer-Cognition:
, psychomotor fatigue
concentration (interest/pleasure)
guilt, suicidal, worthlessness,
mood
Amyg - Answer-guilt, suicidal, worthless, mood
Pre frontal cortex - Answer-cog. symptoms
trouble concentration
decrease pleasure
fatigue
guilt
NA - Answer-pleasure, fatigue, anxiety
Depression & Remission : least difficult - Answer-depressed mood
SI
psychomotor retardation
Depression & Remission : most difficult (common) - Answer-Residual symptoms:
insomnia, fatigue, pain
Reduced Positive Affect - Answer-DA and NE dysfunction
-mood, loss of happiness, loss of interest/pleasure, loss of energy, decreased alertness,
decreased self-confidence
YOU NEED TO INCREASE DA AND NE
Increased Negative Affect - Answer-NE and 5HT dysfunction
- depressed mood, guilt, hostility, aggression, anxiety, irritability, lonliness.
YOU NEED TO INCREASE SEROTONIN AND NE
SSRIs work by selectively and potently inhibiting serotonin reuptake - Answer-Stops
serotonin from being increased back into the presynaptic neuron
SSRI 4 SSSS - Answer-Stomach upset
Sexual Dysfunction
Serotonin Syndrome
Suicidal Ideation
SSRIs - Answer-insomnia, GI, sexual, Serotonin syndrome
TCA - Answer-sedation, anticholinergic (dry), cardio toxic
MAOI - Answer-Insomnia, wt gain, HTN, DRI, tyramine effet
Prozac - Answer-5HT2C antagonism (increases release of NE and DA)
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