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Exam (elaborations)

RNSG 1443 Exam 1 Questions And Answers Latest Update

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RNSG 1443 Exam 1 Questions And Answers Latest Update

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  • October 31, 2024
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  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • RNSG 1443
  • RNSG 1443
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Solution 2024/2025
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RNSG 1443 Exam 1 Questions And Answers
Latest Update

Cancer

uncontrolled and unregulated growth of cells that occurs in people of all
ages; dysfunction of cellular proliferation and differentiation

Protooncogenes

Normal cellular genes that regulate cell proliferation and differentiation that
can become oncogenes when there are mutations

Tumor suppressor genes

A gene whose protein product inhibits cell division, thereby preventing the
uncontrolled cell growth that contributes to cancer.

Oncogenes

cancer causing genes; changes cell that was supposed to die from normal to
malignant and produce a substance called tumor markers, which can be
detected in blood to track healing progress

Three stages of cancer

1. Initiation
2. Promotion
3. Progression

Initiation (cancer)

occurs due to mutation in genes; any change in the DNA, can be inherited
(5-10%) or acquired

Carcinogen

cancer causing agent capable of producing cell alterations; normally the
body takes care of it

, Solution 2024/2025
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Chemical carcinogens

Certain medications, insecticides, industrial dyes, benzene, arsenic,
smoking, formaldehyde, asbestos

Radiation carcinogens

UV rays, X-rays, radiologists, tanning beds

Viral carcinogens

-Human pappilomavirus (HPV)
-Hepatitis B Virus
- Epstein-Barr virus
-HIV

Lifestyle carcinogens

diet, alcohol, nitrate consumption, age, H. pylori

Risk factors for promotion of cancer

- tobacco use
- unhealthy diet
- physical inactivity
- obesity
if any of these factors are denied, then you can halt the progression or
reverse it

Latent period

time between the initial genetic mutation and the clinical evidence of
cancer; can be anywhere from one to fourty years

Progression stage of cancer

rapid cancer growth
tumor angiogenesis
detachment
invasion of surrounding tissues
penetrate lymph/vascular vessels
travel to distant site

, Solution 2024/2025
Pepper
Metastasis

spread of cancer cells beyond original site; can go through blood or lymph -
must endure turbulent blood flow and host's immune system

Sentinel lymph node

first node that receives draining from a body area suspected of having a
tumor

Skip metastasis

The tumor cells may bypass regional lymph nodes and travel to more
distant lymph nodes.

Common sites of metastasis

- brain and cerebrospinal fluid
- lung
- liver
- adrenals
- bone

Tumor-associated antigens (TAAs)

the altered cell surface antigens found on cancer cells.

Immunologic surveillance

the response of the immune system to antigens of the malignant cells

Risk factors for weakening immune response

- stress
- depression
- increased age
- pregnancy
- chronic disease
- chemotherapy for primary cancer

Types of tumor markers

- carcinoembryonic antigen (CEA)
- alpha fetoprotein (AFP)

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