PSIO 303 Exam 3/Final Questions and
Answers
What are the core components of metabolic syndrome? - ANSWER-1. Visceral or central obesity
2. Insulin resistance
3. Hyperinsulinemia
4. Glucose intolerance
5. Dyslipdemia
6. Essential hypertension
Visceral/Central obesity is associated with what ...
How does Skeletal muscle aid in glucoregulation - ANSWER✔✔-- 40% of body mass
- responsible for peripheral disposal of glucose in response to oral glucose/meals
- glucose transport into muscle via myocytes = highly regulated process stimulated by insulin or
contractions
- Glucose molecules transported can be stored as glycogen or oxidized to make ATP
How does the Liver aid in glucoregulation? - ANSWER✔✔-- Site of glucose disposal from hepatic portal
circulation and from general circulation
- Critical site of glucose production (mediate by breakdown of glycogen stores and synthesis of new
glucose from precursor molecules)
- Glycogenolysis and gluconeogenesis (HGP) are under control by hormonal factors (glucagon and
insulin) in accordance to blood glucose level
What is HGP mediated by? - ANSWER✔✔-1. Breakdown of glycogen stored in liver (glycogenolysi)
2. Synthesis of new glucose molecules (gluconeogenesis)
How does the Pancreas aid in glucoregulation? - ANSWER✔✔-- Exocrine and endocrine aspects
(endocrine consists of different cel types = critical for normal glucoregulation (alpha and beta cells)
- beta cells: synthesize and secrete insulin (has effect on glucose transport and storage in cells)
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