,1. A patient with chronic heart failure is prescribed Digoxin.
Which mechanism of action is primarily responsible for its
therapeutic effect?
- A) Inhibition of angiotensin-converting enzyme
- B) Blockade of beta-adrenergic receptors
- C) Inhibition of sodium-potassium ATPase
- D) Stimulation of nitric oxide release
Answer: C) Inhibition of sodium-potassium ATPase
Rationale: Digoxin works by inhibiting the sodium-
potassium ATPase pump, leading to an increase in
intracellular calcium and enhanced cardiac contractility.
2. In managing Parkinson's disease, the rationale for using
Levodopa is that it:
- A) Decreases acetylcholine levels
- B) Increases dopamine levels in the brain
- C) Prevents oxidative stress in neurons
- D) Blocks NMDA receptors
Answer: B) Increases dopamine levels in the brain
Rationale: Levodopa acts as a precursor to dopamine,
thereby increasing dopamine levels and improving
symptoms in Parkinsonian patients.
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