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COMSAE ALL QUESTIONS WITH GUARANTEED ACCURATE ANSWERS

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COCAINE intoxication - ACCURATE ANSWERS impaired judgement, pupil dilate, hallucination (coke bugs) sudden cardiac death; paranoid ideations, angina Tx: alpha blockers/ benzos caution B block bc can cause unopposed alpha Osteoporosis histo - ACCURATE ANSWERS trabecular and cortical bone lose...

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  • October 29, 2024
  • 44
  • 2024/2025
  • Exam (elaborations)
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  • comsae all questions
  • COMSAE
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COMSAE ALL QUESTIONS 20
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COMSAE ALL QUESTIONS 2024\2025 WITH GUARANTEED ACCURATE ANSWERS




COCAINE intoxication - ACCURATE ANSWERS✔✔ impaired
judgement, pupil dilate, hallucination (coke bugs) sudden cardiac death;
paranoid ideations, angina


Tx: alpha blockers/ benzos
caution B block bc can cause unopposed alpha


Osteoporosis histo - ACCURATE ANSWERS✔✔ tra b ecular and
cortical b one lose mass and interconnection despite normal b one
mineralization


assoc w/ Colles fracture- distal radial fracture ; fracture of femoral nec k

,Gilbert Syndrome - ACCURATE ANSWERS✔✔ mild dec UDP
glucuronosyltransferase conjugation and impaired bilirubin uptake;
asymptomatic or mild jaundice>> inc unconjugated bilirubin w/o
hemolysis ; w/ fasting and stress


Crigler Najjar - ACCURATE ANSWERS✔✔ ABSENT UDP
glucuronsyltransferase ; early in life ; die fe w years


find: jaundice, kernicterus (in brain) inc unconjugated bilirubin;


tx: plasmapheresis and phototherapy; type II respond phenobarbital


Du b in Johnson - ACCURATE ANSWER S✔✔ Conjugated
hyper b iliru b inemia b/ c defective liver e xcretion ;
grossly b lac k liver
Benign


Rotor syndrome - ACC URATE A N SWER S ✔✔ milder in presentation
w/ o b lac k liver


impaired hepatic uptake and excretion


w ilson Disease - ACC URATE A N SWER S ✔✔ copper transporting
ATPase ; ATP 7B on Chromosome 1 3

,s/s: before 40 yo, liver dz, neurodisease, psych dz, Kayser Fleischer
ring, hemolytic anemia, renal dz;
find: dec serum ceruloplasmin, inc urine copper
tx: chelation w/ penicillamine or Tridentine, oral zinc


Hemochromatosis - ACC URATE A N SWER S ✔✔ recessive, HFE,
chromosome 6; a bnormal iron sensing, increase intestinal a bsor b


find: inc ferritin, inc iron, dec TIBC, inc transferrin saturation
identify w/ Prussian b lue stain / liver MRI


Hemochromatosis finds - ACC URATE A N SWER S ✔✔ after age 4 0
>2 0 iron;
triad: cirrhosis, DM, skin pigmentation; dilated cardiomyopathy,
hypogonadism, arhtropathy ; HCC is common cause death


Treatment Hemochromatosis - ACC URATE A N SWER S ✔✔ repeat
phle b otomy, chelation deferasiro x, defero xamine, oral deferiprone


Wolff Parkinson White Syndrome - ACCURATE ANSWERS✔✔ MC
ventricular pre e x citation syndrome


a b nml fast atria to ventricle (b undle of Kent ); b ypasses AV node > >
ventricles b egin partially depolari zation earlier (NOTED BY DELTA
WAVE ON EKG) w idened Q R S and shortened PR

, Conduction pathway heart - ACC URATE A N SWER S ✔✔ SA node >
atira > AV node > b undle HIS, R and L b undle b ranches > pur kinje
fi bers > ventricles


L branch anterior/posterior fascicles


Edema - ACC URATE A N SWER S ✔✔ inc capillary pressure
dec plasma proteins (dec oncotic capillary pressure)
inc capillary permea bility
increase interstitial fluid colloid oncotic pressure


Celiac Disease - ACC URATE A N SWER S ✔✔ setting: 14 mo kid losing
w eight eating lots of foods ;


histology: crypt abnormalities (hyperplasia); villous atrophy,
lymphocytic infiltration


presents as mala b sor btion (diarrhea etc in kids )
in adults= short stature, anemia delayed puberty


Musculocutaneous nerve C 5- C 7- ACC URATE A NSWER S✔✔
upper trunk compression cause injury; loss forearm flexion/supination;
loss sensation over lateral forearm


A x illary nerve C 5 - C 6 - ACC URATE ANSWER S✔✔ flat deltoid ;
loss arm a bduction, loss sensation over deltoid and lateral arm

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