100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
NBME Final – Biochem Exam Questions and Answers 100% Pass $10.49   Add to cart

Exam (elaborations)

NBME Final – Biochem Exam Questions and Answers 100% Pass

 4 views  0 purchase
  • Course
  • NBME
  • Institution
  • NBME

NBME Final – Biochem Exam Questions and Answers 100% Pass Lesch-Myhan syndrome - answer- X-linked recessive - absent *HGPRT* (hypoxanthine guanine phosphoribosyl transferase) (hypoxanthine --> IMP & guanine --> GMP) - excess *uric acid* *H*yperuricemia (orange "sand" in diaper) *G*ou...

[Show more]

Preview 2 out of 14  pages

  • October 29, 2024
  • 14
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NBME
  • NBME
avatar-seller
Brightstars
©BRIGHTSTARS EXAM SOLUTIONS
10/22/2024 12:14 PM


NBME Final – Biochem Exam Questions and
Answers 100% Pass


Lesch-Myhan syndrome - answer✔- X-linked recessive
- absent *HGPRT* (hypoxanthine guanine phosphoribosyl transferase)
(hypoxanthine --> IMP & guanine --> GMP)
- excess *uric acid*


*H*yperuricemia (orange "sand" in diaper)
*G*out
*P*issed off (aggression, self-mutilation)
*R*etardation
Dys*T*onia

Adenosine deaminase deficiency - answer✔- toxicity in lymphocytes
- autosomal recessive SCID

Irinotecan/topotecan - answer✔inhibit eukaryotic topoisomerase I

Etoposide & Camptothecins - answer✔- antineoplastic agent, chemotherapy
- inhibits eukaryotic topoisomerase (DNA replication)

Fluoroquinolones inhibit... - answer✔prokaryotic topoisomerase II (DNA gyrase) &
topoisomerase IV
Xeroderma pigmentosum: defective _______

Lynch syndrome (HNPCC): defective _____ - answer✔XP: NER
HNPCC: MMR

, ©BRIGHTSTARS EXAM SOLUTIONS
10/22/2024 12:14 PM

Defective in ataxia telangiectasia, breast/ovarian
cancers with BRCA1 mutation, and Fanconi

anemia - answer✔Non-homologous end joining

α-amanitin - answer✔- cancer drug
- death cap mushroom
- inhibits eukaryotic RNA pol (transcription)

actinomycin D - answer✔- cancer drug
- inhibits RNA pol (transcription) in euk & prok
(intercalates in between bases & blocks RNA pol)

Rifampin - answer✔- inhibits RNA pol (transcription) in prokaryotes
- used to treat TB

Tay Sachs - answer✔- lysosome storage disorder
- deficient he*X*osaminidase *A* (T*A*y-Sa*X*)
- progressive neurodegeneration & developmental delay
- *"cherry red" spot on macula*

Zellweger's syndrome - answer✔- peroxisome disease
- autosomal recessive
- hypotonia, seizures, flat face, hepatomegaly, early death (usually < 6mo)

Colchicine - answer✔- used to treat *Gout*
- acts on microtubles (mitotic blocker)

Vincristine/Vinblastine - answer✔- cancer drugs
- "freezes" microtubules (metaphase blocker)

Taxol (paclitaxel) - answer✔- cancer drugs
- stabilizes microtubules (metaphase blocker)
Kartagener syndrome

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller Brightstars. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $10.49. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

75632 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$10.49
  • (0)
  Add to cart