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Mbg 2040 Quiz 9 with 100- correct answers 2025
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Mbg 2040 Quiz 9 with 100- correct answers 2025
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Mbg 2040 Quiz 9 with 100%correct answers 2025
The movement of a hydrogen atom from one position on an organic
molecule to another position on the same molecule is called a: - answer
Tautomeric shift
The widely used method for screening chemicals for mutagenicity is
called: - answer The ames test
The SOS response in E.coli functions to replace damaged regions of DNA
but is a highly error prone process which results in a large number on
mutations. - answer True
Spontaneous mutations occur relatively frequently but often they are
silent, that is they do not produce a phenotypic change. - answer False
Which of the following is an example of a mutagen that acts by donating
alkyl groups to the bases in DNA? - answer Mustard gas
Some mutations have no effect on phenotype, alleles with these mutations
are called: - answer Iso-alleles
Which of the following is NOT a factor which influences the rate of
spontaneous mutation? - answer Environmental/selective pressure
Which of the following chemical mutagens is most likely to cause a
transversion mutation? - answer Proflavin
Which of the following pieces of evidence/statements supports the
concept that "Mutation is non-adaptive"? - answer Mutations conferring
antibiotic resistance in bacteria are present before exposure to the
antibiotic
, Put the following steps of the E.coli Nucleotide excision repair mechanism
in order: - answer 1. Uvr trimer (2 x UvrA and 1 x UvrB) recognises and
binds the damaged DNA.
2. One molecule of ATP is cleaved and energy is used to bend the DNA at
the damaged site; UvrB changes confirmation and the UvrA dimer is
released.
3. UvrC binds the DNA/UvrB complex and cleaves a phosphodiester bond
on either side of the damaged DNA.
4. DNA helicase II releases the excised oligomer. DNA polymerase I
replaces missing nucleotides and DNA ligase seals the nick at the 3' end of
the newly synthesised DNA.
The following DNA sequence 5' -TGCGATCC - 3' is mutated to produce 5' -
TGCGATAC - 3'.
This is an example of which type of mutation? - answer Transversion
UV irradiation causes breaks in chromosomes which can lead to many
different chromosomal abnormalities such as translocations, duplication
and large scale deletions. - answer False
Which of the following chemical mutagens act via it's ability to incorporate
into DNA by replacing a base during replication and causing mispairing in
future replication? - answer 5-bromouracil
1.________ is the ultimate source of genetic variation, 2.__________ provides
new genetic combinations and 3._________ preserves those genetic
combinations which lead to the most reproductive success in a particular
environment. - answer 1. Mutation
2. Recombination
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