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AAMC Sample Test Bio/Biochem Practice Questions and Answers

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AAMC Sample Test Bio/Biochem Practice Questions and Answers Hydrolysis of the γ phosphate of GTP bound to Arf1 results in: A.denaturation. B.activation. C.inactivation. D.membrane association. - ANSWER-C.inactivation. hydrolysis of GTP would result in the formation of GDP in the pocket, whi...

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  • October 28, 2024
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AAMC Sample Test Bio/Biochem Practice

Questions and Answers


Hydrolysis of the γ phosphate of GTP bound to Arf1 results in:




A.denaturation.


B.activation.


C.inactivation.


D.membrane association. - ANSWER✔✔-C.inactivation.




hydrolysis of GTP would result in the formation of GDP in the pocket, which, based on the information in

the passage, is the inactive form.


The Arf1-activating molecule GTP is most closely related to which family of biomolecules?




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A.Nucleotides


B.Amino acids


C.Lipids


D.Carbohydrate - ANSWER✔✔-A. Nucleotides




GTP stands for guanosine tri-phosphate, which is a nucleotide.


GAP belongs to what class of enzymes?




A.Transferase


B.Phosphatase


C.Kinase


D.Isomerase - ANSWER✔✔-Mistake!




I chose A and its B




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GTPase Activating Protein




phosphatases are a class of hydrolase responsible for the cleavage of phosphate bonds utilizing water to

remove a molecule of inorganic phosphate.


Proteins that are encapsulated in Arf1-COP derived vesicles are bound for the:




A.endoplasmic reticulum.


B.cellular membrane.


C.nucleus.


D.cytosol. - ANSWER✔✔-A. ER




Arf1-COP undergoes retrograde transport. Protein translation principally occurs in the endoplasmic

reticulum (ER). The proteins are then transported to the Golgi apparatus for post translational

modification, processing, and packaging for proper localization. Retrograde transport would reverse the

motion and return the protein to the ER.


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protein translaiton - ER


protein post-translation - golgi


Based on the mode of action described for BFA in the passage, the drug would be most effective against:




A.eukarya.


B.viruses.


C.bacteria.


D.archaea. - ANSWER✔✔-A.




BFA disrupts the Golgi apparatus, and of the choices, only eukaryotes have a Golgi apparatus


Which of the following experiments would provide the best supporting evidence that neutrophils are the

cause of the reperfusion injury?




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