Advanced Pharmacology Mock
Rehearsal Exam| 2025/2026 Certification|
Verified Q&A
1. What term describes the fraction of an administered drug that reaches the systemic circulation?
Bioavailability
2. Which pharmacokinetic phase involves the movement of drugs from the bloodstream to the
tis...
1. What term describes the fraction of an administered drug that reaches the systemic circulation?
Bioavailability
2. Which pharmacokinetic phase involves the movement of drugs from the bloodstream to the
tissues?
Distribution
3. In pharmacodynamics, what term describes the maximum effect a drug can produce,
regardless of dose?
Efficacy
4. Which process describes the body's ability to change drug concentration through liver
enzymes?
Metabolism
5. For drugs administered orally, which organ is primarily responsible for first-pass metabolism?
Liver
1
,6. What term refers to the time required for a drug’s plasma concentration to reduce by half?
Half-life
7. Which CYP450 enzyme is most commonly involved in drug metabolism and can affect many
medications?
CYP3A4
8. In pharmacogenomics, which gene variant is linked to slower metabolism of certain drugs,
such as antidepressants?
CYP2D6
9. Genetic testing for the HLA-B*5801 allele is essential before initiating which drug to avoid
severe reactions in specific populations?
Allopurinol
10. Warfarin dosing is often adjusted based on genetic testing for which two genes?
CYP2C9 and VKORC1
11. Which enzyme deficiency could result in hemolysis in patients taking drugs like primaquine?
G6PD
12. Why should geriatric patients often receive lower doses of renally excreted drugs?
2
, Reduced renal clearance
13. Which process is typically reduced in elderly patients, impacting the elimination of certain
drugs?
Glomerular filtration rate (GFR)
14. For pediatric patients, which pharmacokinetic phase is slower due to immature enzyme
activity?
Metabolism
15. Which medication is contraindicated in pregnancy because it can cause fetal malformations?
Isotretinoin
16. A patient has overdosed on acetaminophen. Which antidote should be administered to prevent
liver damage?
N-acetylcysteine
17. In the case of benzodiazepine overdose, what is the primary antidote?
Flumazenil
18. Which toxicity is a concern when giving high doses of aspirin, especially in children?
Reye’s syndrome
3
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller AceTests. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $9.99. You're not tied to anything after your purchase.
