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Inflammation NURS 5315 Exam with correct answers
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Inflammation NURS 5315 Exam withcorrect answers
cellular injury leads to: (5) - correct answer -1. coagulation cascade activation
2. Kinin system activation
3. Mast cell degranulation
4. Complement cascade activation
5. chemotactic factors released
Coagulation cascade activation leads to (4) - correct answer -fibrin mesh containing
the injury
traps microorganisms to prevent spread
stops bleeding
plasmin-activates complement and kinin system
Kinin system activation leads to (4) - correct answer -Bradykinin released:
pain
vasodilation/permeability
chemotaxis
Complement cascade activation leads to (5) - correct answer -MAC-lysis of bacteria
C2B--increased vasodilation and permeability
C3a/C5a/C4a--triggers mast cell degranulation
C5a attracts neutrophils
C3b enhances opsonization
,C2B does what?
and is apart of what chain - correct answer -increases vasodilation and permeability
complement cascade activation
MAC does what?
and is apart of what chain? - correct answer -lysis of bacteria
complement cascade activation
C5a does what?
and is apart of what chain? - correct answer -Attracts neutrophils
complement cascade activaton
C3b does what?
and is apart of what chain? - correct answer -Enhances opsonization
complement cascade activation
Chemotactic factors released leads to what? - correct answer -attraction of
neutrophils, eosinophils and monocytes
phagocytosis (leads to WBC death/rupture)
-Activates complement, kinin and coagulation cascade
, monocytes present antigens and activate T/B cell immunity--release cytokines Il 1,
IL 6, TNF and growth factors
monocytes present antigens and activate T/B cell immunity--release cytokines Il 1,
IL 6, TNF and growth factors
happens in which chain - correct answer -Chemotactic factors released
Mast cell degranulation leads to: (5) - correct answer -Histamine
cytokines
leukotrienes
prostaglandins
platelet activating factor
histamine does what? - correct answer -vasodilation/increased permeability
increased blood flow to site
local swelling/erythema
cytokines do what (in mast cell degranulation) - correct answer -TNF--leukocyte
emigration, inc permeability
IL 13--chemotaxis, B cell proliferation and antibody productuon
IL4--Bcel proliferation and antibody production
Which interlukin is elevated early in inflammation? - correct answer -IL4
Which interlukin is elevated later in inflammation? - correct answer -IL 13
TNF released when in inflammation process? - correct answer -early and late
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