ASCP HEMATOLOGY EXAM REVIEW QUESTIONS
WITH COMPLETE CORRECT ANSWERS | GRADE A+ Name the locations of active marrow in adults:
Ans: sternum, skull, ribs, pelvis, vertebrae
Where does hematopoiesis take place during the first 2 months of gestation?
Ans: yolk sac
Where does the majority of hemat...
Which growth factors stimulate the erythrocyte lineage?
Ans: GM-CSF, EPO, IL-3
Which growth factors stimulate the granulocyte lineages?
,Ans: GM-CSF, IL-3
Which growth factors stimulate the platelet lineage?
Ans: GM-CSF, IL-3, TPO
Which growth factors stimulate the lymphocyte lineage?
Ans: IL-2, IL-4, IL-6, IL-7
Which protein functions in the transport of Fe?
Ans: transferrin
What is the major storage form of Fe?
Ans: ferritin
What is the long-term (H20) insoluble Fe storage form called?
Ans: hemosiderin
Excess Iron is stored where? What does this cause?
Ans: tissues and body organs, hemosiderosis, hemochromatosis
, Porphyrias are attributed to?
Ans: excessive formation of porphrins due to blockages in any enzymatic step in the heme
synthesis pathway.
Red or port wine colored urine can be seen in which condition related to the build up of heme
precursors?
Ans: porphyria
Neuropsychiatirc symptoms are seen when a build up of which precursors occurs?
Ans: early precursors (Delta-aminolevulinic acid/Porphobilinogen)
Cutaneous symptoms such as photo-sensitivity and facial hair are seen when a build up of
which precursors occurs?
Ans: later precursors (uroporphyrinogen/coproporphyrinogen, protoporphyrin/heme)
Synthesis of heme requires what two components?
Ans: iron, protoporphyrin
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