NURS549 Final Exam Study Guide
Solutions
2 Monoclonal immunosuppressive Antibody Drugs - Ans:-Daclizumab(zenapax)- Reduces activated T-
cell numbers and activities by binding to interlukin
Muromonab(orthoclone)-Binds to CD3 receptors on T cells and disrupts function. Depletes circulating T
cel...
Interferon free antiviral drugs - Ans:✔✔-Viekira Pak-Ombitasvir - is a NS5A inhibitor with potent
pangenotypic picomolar antiviral activity. ( a zinc-binding and proline-rich hydrophilic phosphoprotein
that plays a key role in Hepatitis C virus RNA replication)
Paritaprevir - is an inhibitor of the NS3/4A serine protease. (The NS3/4A serine protease is required for
self-cleavage during viral replication, but may also inhibit activation of interferon signalling pathways in
infected cells )
Dasabuvir - non-nucleoside NS5B polymerase inhibitor. ( has the key function of replicating the HCV's
viral RNA )
Sofosbuvir - ( Solvadi )
Ledipasvir + Sofosbuvir ( Harvoni )
Simeprevir ( Olysio)
Daclatasvir ( Daklinza )
90% cure rate
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