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NUR968: RBC Physiology & Pathophysiology Exam Study Guide Solutions

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NUR968: RBC Physiology & Pathophysiology Exam Study Guide Solutions __: is the aqueous (water) medium or fluid part of the blood - Ans:-Plasma What substances are dissolved in plasma? (10) - Ans:-1. Electrolytes 2. Proteins 3. Lipids 4. Carbohydrates 5. Amino acids 6. Vitamins 7. Hormones...

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  • October 24, 2024
  • 62
  • 2024/2025
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  • NUR 2024/2025
  • NUR 2024/2025
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NUR968: RBC Physiology &
Pathophysiology Exam Study Guide
Solutions


__: is the aqueous (water) medium or fluid part of the blood - Ans:✔✔-Plasma


What substances are dissolved in plasma? (10) - Ans:✔✔-1. Electrolytes


2. Proteins


3. Lipids


4. Carbohydrates


5. Amino acids


6. Vitamins


7. Hormones


8. Urea


9. Uric acid

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10. Oxygen, carbon dioxide & nitrogen


True or false: Red blood cells, white blood cells & platelets are all suspended in plasma - Ans:✔✔-True


In the plasma, what helps maintain osmolarity? - Ans:✔✔-The ions


What is the chief CATION in the plasma? - Ans:✔✔-Sodium (Na+)


What is the chief ANION in the plasma? - Ans:✔✔-Chloride (Cl-)


Many different proteins are dissolved in the plasma. The most abundant is what? - Ans:✔✔-Albumin


What does albumin do? - Ans:✔✔-Provides the critical osmotic or oncotic pressure that regulates the

movement of water in & out of the vascular space




-Think back to Starling's forces


What does the loss of plasma proteins into the extravascular space result in? (4) - Ans:✔✔-1. Ascites


2. Edema in closed cavities


3. Pleural effusions (lungs)


4. Pericardial effusions (heart)




Page 2/62

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What is the second largest group of plasma proteins? - Ans:✔✔-Immunoglobulins


True or false: Other plasma proteins include the clotting factors, components of the compliment cascade

(part of the immune system), enzymes, enzyme inhibitors & many others - Ans:✔✔-True


The RBC is a "bag" containing fluid & hemoglobin. The RBC takes on a BICONCAVE shape with an average

diameter of __ micrometers - Ans:✔✔-7 micrometers




-RBC's can change shape & squeeze through capillaries (smaller than 7 micrometers)


What is the lifespan of a RBC? - Ans:✔✔-120 days


Do RBCs contain a nucleus or mithochondria? - Ans:✔✔-No!


RBCs contain no nucleus or mitochondria yet they contain enzymes that are able to produce enough ATP

to: (4) - Ans:✔✔-1. Maintain ion composition


2. Maintain the cell membrane


3. Keep iron in the cell in the ferrous form (Fe+2) form which binds oxygen as opposed to the ferric

(Fe+3) form which does not bind oxygen


4. Prevent oxidation of the proteins in the RBC




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FIRST PUBLISH OCTOBER 2024




What happens to the metabolic systems of the RBC as they age? - Ans:✔✔-The metabolic systems of the

RBC become progressively LESS ACTIVE as they age thus, the cells become more fragile with age


Many RBCs self-destruct in the __ - Ans:✔✔-Spleen


True or false: Remember that the spleen has capillaries the size of 3 micrometers, thus the RBC must fold

like a taco to squeeze through. This is not a problem if the cell is healthy, but becomes a problem when

the membrane is fragile - Ans:✔✔-True


So how big are the capillaries of the spleen? - Ans:✔✔-3 micrometers




-RBCs are 7 micrometers


-They must fold up & squeeze through


-Not a problem unless the RBC membrane is fragile


What happens when the spleen is removed? - Ans:✔✔-When the spleen is removed, the number of

abnormally old RBC's greatly increase




-As an old RBC becomes frail, it will fall tear apart




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