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Campylobacter & Helicobacter

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Campylobacter & Helicobacter General Characteristics Common to Superfamily  Gram-negative  Helical (spiral or curved) morphology; Tend to be pleomorphic  Characteristics that facilitate penetration and colonization of mucosal environments (e.g., motile by polar fl...

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  • October 23, 2024
  • 59
  • 2024/2025
  • Exam (elaborations)
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angelamakinyaa
,Campylobacter &
Helicobacter

, General Characteristics
Common to Superfamily
 Gram-negative
 Helical (spiral or curved) morphology; Tend to be
pleomorphic
 Characteristics that facilitate penetration and
colonization of mucosal environments (e.g.,
motile by polar flagella; corkscrew shape)
 Microaerophilic atmospheric requirements
 Become coccoid when exposed to oxygen or
upon prolonged culture
 Neither ferment nor oxidize carbohydrates

, History of Campylobacter
 First isolated as Vibrio fetus in 1909 from
spontaneous abortions in livestock
 Campylobacter enteritis was not recognized
until the mid-1970s when selective isolation
media were developed for culturing
campylobacters from human feces
 Most common form of acute infectious
diarrhea in developed countries; Higher
incidence than Salmonella & Shigella combined
 In the U.S., >2 million cases annually, an annual
incidence close to the 1.1% observed in the
United Kingdom; Estimated 200-700 deaths

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