what is acetominophen used for - ANSWER mild to moderate pain
does acetaminophen have anti-inflammatory activity - ANSWER no
onset of acetaminophen - ANSWER 30 minutes
FDA daily maximum of acetaminophen - ANSWER 4000 mg
FDA recommendation for daily maximum of acetaminophen - ANSWER 3000-3250 mg
what is the daily maximum of acetaminophen for those at increased risk of
hepatotoxicity - ANSWER 2000 mg
extra strength (500 mg) acetaminophen dosing - ANSWER 2 tabs every 6 hours
6 tabs max daily
pediatric dosing of acetaminophen - ANSWER 10-15 mg/kg every 4-6 hours
what form does pediatric acetaminophen come in - ANSWER 160 mg/5 mL suspension
how does acetaminophen lead to hepatotoxicity - ANSWER some of the acetaminophen
enters CYP450 oxidase system to form NAPQi which can lead to hepatocellular necrosis
is there is too much
,max dose for children taking acetaminophen - ANSWER 5 doses in 24 hours
how many alcoholic drinks can you have when taking acetaminophen - ANSWER less
than 3 or at risk for liver damage
extreme issues that can be caused by acetaminophen - ANSWER stevens-johnson
syndrome and toxic epidermal necrolysis
NSAID - ANSWER non-steroidal anti-inflammatory drug
over the counter NSAIDs - ANSWER ibuprofen and naproxen
how do NSAIDS help inflammation - ANSWER central and peripheral inhibition of
prostaglandins
ibuprofen adult dosing - ANSWER 200-400 mg every 4-6 hours
naproxen adult dosing - ANSWER 220 mg every 8-12 hours
who cannot take naproxen - ANSWER children under 12
pediatric dosing of ibuprofen - ANSWER 5-10 mg/kg every 6-8 hours
who cannot take pediatric ibuprofen - ANSWER under 6 months old
NSAID GI complications - ANSWER bleeding, ulcers, constipation
,risk factors for GI bleeding from nsaids - ANSWER history of peptic ulcer disease,
history of GI bleed, NSAID dose, advanced age, corticosteroids and anticoagulant use,
alcohol use, long term usage
1st recommendation for analgesic for patient with cardiovascular disease - ANSWER
acetaminophen
2nd recommendation for analgesic for patient with cardiovascular disease - ANSWER
naproxen
what factors increase the risk of renal toxicity from NSAIDs - ANSWER advanced age,
hypertension, diabetes, cardiovascular disease, diuretic use
renal precautions for NSAIDs - ANSWER patients with impaired renal function,
congestive heart failure, or other disease related to impaired renal function
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