Positive symptoms: (reflect the development of the symptoms of psychosis). - ANSWER
- Dramatic, reflect loss of touch with reality:
pg. 1
,Delusions Hallucinations Distortions or exaggerations in language and communication
disorganized speech disorganized behavior Catatonic behavior Agitation
Negative symptoms (reflect loss of normal function and feeling): - ANSWER - Losing
interest in things
Not able to experience pleasure: adenine
Blunted affect
Emotional withdrawal
Poor rapport
Apathy
Alogia: restriction in fluency or productivity of thought and speech
Avolition: restrictions in initiation of goal directed behavior
Malfunction of neocortical circuits and may also involve mesolimbic regions such as -
ANSWER - nucleus accumbent
Nucleus accumbent responsible for: (2) - ANSWER - reward and motivation. Increased
rate of substance uses and abuse.
The dopamine hypothesis of schizophrenia postulates that hyperactivity of
________receptor neurotransmission in ________ and ____ brain regions contribute to
_______ symptoms of schizophrenia - ANSWER - - D2 receptor neurotransmission in
-subcortical and limbic brain regions contributes to positive symptoms of schizophrenia,
The dopamine hypothesis of schizophrenia postulates that negative and cognitive
symptoms of this disorder can be attributed to ____ of __ receptor in the _____ ____ -
ANSWER - hypo functionality of dopamine D1 receptor neurotransmission in the
prefrontal cortex
Role of neocortical pathway in schizophrenia: to send ____ to areas of the _______
_____ - ANSWER - Axons to areas of the prefrontal cortex
Axons sent via the neocortical pathway mediate _________ symptoms in the DLPFC
and _______ symptoms in the VMPFC - ANSWER - cognitive symptoms and affective
Dorsolateral prefrontal cortex (DLPFC) mediates __________ symptoms of
schizophrenia due to _____ of the neocortical dopamine pathway. - ANSWER - negative
symptoms
Hypoactivity
Negative symptoms mediated by DLPFC - ANSWER - Apathy
Cognition
VMPFC mediates Negative and affective symptoms associated with schizophrenia due
to - ANSWER - Hypoactivity
Affective symptoms of schizophrenia - ANSWER - dysphoria, suicidality, hopelessness
negative symptoms of schizophrenia - ANSWER - disturbance of affect, blunting (severe
reduction in the intensity of affect expression), flat affect, inappropriate affect (might
laugh hysterically while describing someone’s death)
negative symptoms of schizophrenia - ANSWER - the absence of appropriate behaviors
(expressionless faces, rigid bodies)
pg. 4
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller ASSIGNMENT7. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $13.99. You're not tied to anything after your purchase.
