Keflex(cephalexin) - Answer 500mg PO, Disp 28 1 po q 12 hrs.
For staph and strep, and limited anaerobes
NO MRSA coverage
Augmentin(amoxicillin/clavulante) - Answer 875/125 mg, Disp 28, 1 po q 12 hrs.
For staph (no MRSA)
Improved coverage for PCN resistant anaerobes not covered by Keflex.
Ance...
Keflex(cephalexin) - Answer 500mg PO, Disp 28 1 po q 12 hrs.
For staph and strep, and limited anaerobes
NO MRSA coverage
Augmentin(amoxicillin/clavulante) - Answer 875/125 mg, Disp 28, 1 po q 12 hrs.
For staph (no MRSA)
Improved coverage for PCN resistant anaerobes not covered by Keflex.
Ancef(cefazolin) - Answer 1 gram IV preoperatively for surgery prophylaxis 30 to 60 min
prior to surgery per SCIp protocols. Larger pt's may require 2 gram.
Cipro - Answer 500 mg, Disp 28, 1 po q 12 hrs.
For Soft tissue infection gram + and (-), Anitpseudomal, commonly combined with Clindamycin
for oral antibiotic therapy for broad spectrum coverage of polymicrobial infection seen in the
diabetic foot of pen. allergic pts.
Clocin (clindamycin) - Answer 300mg, disp 56, 1 po q 6hrs.
Soft tissue infection gram positive anaerobic coverage. Commonly combined with cipro. Used
for SCIP protocol bacterial prophylaxis with surgery dosed at 600mg IV.
Bactrim DS (timethoprim/sulfamethoxazole) - Answer 160/800 mg, disp 28, 1 po q 12
hrs.
For soft tissue and bone infection
Effective against MRSA(resistance is increasing)
Doxycycline - Answer 100 mg, Disp 28, 1 po q 12 hrs.
Effective oral for MRSA
Limited side effects.
Good for pts on dialysis, due to being filtered in liver.
Zyvox (linezolid) - Answer 600 mg, Disp 28, 1 po q 12 hrs.
MRSA coverage(east transition from IV in hospital to Oral in outpatient without need for PICC
line.
Expensive
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Coverage for VRE
Can cause thrombocytopenia, must check CBC weekly.
Vancomycin - Answer 1 gram IV q 12 hrs.
MRSA coverage IV
No psuedomonal coverage
Required monitoring of peaks and troughs.
Infuse slowly(45min - 1 hr) to avoid red man syndrome.
Must be given within 2 hrs of incision when utilized for preop prophylaxis.
PO use is only for C. Diff no MRSA
Invanz (ertapenem) - Answer 1 gram EV q 24 hrs.
For skin infections including complicated diabetic foot
Good broad spectrum for diabetic foot without pseudomonas coverage.
No MRSA or psuedomonal coverage.
Zosyn (pipercillin/tazobactam) - Answer 3.375 grams IV q 6 hrs.
Good broad spectrum coverage for diabetic foot with pseudomonas coverage.
No MRSA coverage.
Unasyn (ampicillin/sulbactam) - Answer 3 grams IV q 6 hrs.
For skin and bone infections.
No MRSA or Psuedomonas coverage.
Braod spectrum Gram + and (-), and anaerobes.
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