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Quiz 1 Pharmacology 5334 Questions
and Correct Answers the Latest Update
and Recommended Version
PCN drug-drug interactions
→ -aminoglycosides
→ -bacteriostatic antibiotics
→ -probenecid
Treatment for ONYCHOMYCOSIS
→ Terbinafine (Lamisil) 1 tab daily x 3-6 months po
Best treatment for chlamydia
→ Aziythromycin 1gm 1x dose
→ or
→ Doxycycline 100 mg po twice a day for 7 days
Patient with vaginal candidiasis, what is the treatment?
→ Fluconazole 150mg po once
Treatment for uncomplicated cervical gonorrhea
→ Ceftriaxone, 250 mg IM once, plus azithromycin, 1 g PO once
Patient with tinea capitis, what is the TX?
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→ Very difficult to treat topically
→ Griseofulium po 6-8 weeks
→ or
→ Terbinafine (Lamisil) po 2-4 weeks
Narrow Spectrum PCN
→ PCN G (procaine), PCN G (benzathine), PCN V
→ Bugs they fight: GRAM(+) cocci- 1st drug of choice against Strep (pneumonia,
pharyngitis, endocarditis) , Clostridium (tetanus, anthrax, gas gangrene)Neisseria,
spirochete (syphilis)
Lauren comes into the clinic and is diagnosed with Trichomoniasis. The NP can prescribe:
→ Metronidazole, 2 g PO once or
→ Tinidazole, 2 g PO once
Penicillinase-resistant PCN
→ Oxacillin, Nafacillin, Dicloxacillin
→ Bugs they fight: Staph
Broad spectrum PCN
→ Ampicillin- ampiciliin/sulbactam (Unasyn)
→ Amoxicillin- amoxicillin/ER (Moxatog), Amoxicillin/Clavulanate(Augmentin)
→ Bugs they fight: Good against GRAM (-)H. influenza, e-coli, proteus mirabilis,
enterococci, salmonella and shigella
Extended Spectrum PCNs
→ Piperacillin/tazobactam (Zosyn)
→ Bugs they fight: same as broad spectrum + pseudomonas, klebsiella, bacterial fragilis
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Beta-lactamase inhibitors
→ clavulanic acid, sulbactam, tazobactam
→ **Can not be given on their own, only in combo with PCN's i.e.> Augmentin, Unasyn,
Zoysn
Cephalosporin Generation 1
→ -cephalexin
→ -cephazolin
→ -cephadoxil
→ **Cephlasporinase will destroy**
→ Not the drug of choice for active infections- good for prophylaxis prior to sx
Cephlasporin (2nd generation)
→ Cefuroxime-most common
→ Bugs they fight: h.influenza (pneumonia), otitis sinusitis, res. tract infection
Cephlasporin (3rd generation)
→ Cefotaxime, Cefdinir, Cefixime, Cefodoxime, Ceftaazidime, Ceftibuten, Ceftriaxone
→ **Can penetrate CSF fluid**
→ Bugs they fight: Great against GRAM (-) bacteria causing meningitis, h.influenza,
klebsiella, proteus, salmonella
Cephlasporin (4th generation)
→ Cefepime-hospital associated pneumonia's & Ceftolozone/tozobactam (Zerbaxa)-
complicated UTI's and intraabdominal infections
Cephlasporin (5th generation)
→ Ceftaroline (Teflaro)-MRSA
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