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NU 545 ch 7 Exam Questions With Correct Answers

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NU 545 ch 7 Exam Questions With Correct Answers Cathelicidins - answerFamily of antimicrobial peptides that in humans has one member. Defensins - answerantimicrobial peptides that inhibit microbial growth Mannose-binding lectin (MBL) - answersoluble acute-phase protein in the blood that binds t...

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  • October 18, 2024
  • 17
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NU 545
  • NU 545
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©SIRJOEL EXAM SOLUTIONS
12/3/2024 11:27AM



NU 545 ch 7 Exam Questions With Correct
Answers


Cathelicidins - answer✔Family of antimicrobial peptides that in humans has one member.


Defensins - answer✔antimicrobial peptides that inhibit microbial growth


Mannose-binding lectin (MBL) - answer✔soluble acute-phase protein in the blood that binds to

mannose residues on pathogen surfaces and, when bound, activates the complement system by

the lectin pathway


Resistin-like molecule beta - answer✔Found in intestinal goblet cells, where it appears to protect

against helminth infections.


Antimicrobial lectins - answer✔Lectin (carbohydrate binding protein) family with activity

against Gram+ bacteria; C-type lectins


Bactericidal/permeability-inducing protein (BPI) - answer✔Stored in neutrophils and intestinal

epithelium. Reacts with lipopolysaccharide on the surface of gram-negative bacteria, resulting in

bacterial lysis.

, ©SIRJOEL EXAM SOLUTIONS
12/3/2024 11:27AM


inflammatory response - answer✔nonspecific defense reaction to tissue damage caused by injury

or infection


acute inflammatory response - answer✔series of cellular changes that bring blood to the site of

an injury or infection.

1)vasodilation

2)increased vascular permeability

3)diapedesis


Diapedesis - answer✔Passage of white blood cells through intact vessel walls into tissue


3 plasma protein systems - answer✔complement, clotting, kinin


proenzyme - answer✔an inactive precursor of an enzyme


complement system - answer✔A group of about 30 blood proteins that may amplify the

inflammatory response, enhance phagocytosis, or directly lyse extracellular pathogens.


3 pathways of complement system - answer✔classical, alternative, lectin


classical pathway - answer✔activated by antibodies bound to antigen, which interact with

complement system. Begins with activation of complement protein C1


lectin pathway - answer✔mannose-binding lectin binds to pathogen surface. It is antibody

independent.

, ©SIRJOEL EXAM SOLUTIONS
12/3/2024 11:27AM


Anaphylaxotoxins - answer✔they induce rapid mast cell de granulation and release of histamine,

causing vasodilation and increased capillary permeability. Occur early in inflammation, close to

the inflammatory site.


alternative pathway - answer✔activated by gram negative bacteria and fungal cell wall

polysaccharides


complement cascade - answer✔a precise sequence of events, usually triggered by antigen-

antibody complexes, in which each component of the complement system is activated in turn


antigen-antibody complex - answer✔the complex formed when an antibody binds to an antigen.


C3 convertase - answer✔the enzyme complex that catalyzes a crucial step in complement

activation—the deposition of large numbers of C3 molecules on a cell's surface, which tags the

cell for removal by phagocytes or starts the assembly of the membrane attach complex.


chemotactic factors - answer✔Biochemical substance that attracts leukocytes to the site of

inflammation. Required for a longer period and occurs distal to the inflammatory site.


Carboxypeptidase - answer✔Plasma enzymes that are inactive as anaphylatoxins but retain

chemotactic activity


Opsonins - answer✔Molecules that "tag" microorganisms for destruction by cells of the

inflammatory system (primarily neutrophils and macrophages)

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