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MEDS 530A Pathology Final Exam Questions With Correct Answers

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  • MEDS 530
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  • MEDS 530

MEDS 530A Pathology Final Exam Questions With Correct Answers A 60-year-old man who had generalized atherosclerosis died 24 hours after having a stroke. A cerebral infarct was found at autopsy. Necrosis of the brain is classified as - answerBrain infarcts are characterized by liquefactive necro...

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  • October 18, 2024
  • 9
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • MEDS 530
  • MEDS 530
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sirjoel
©SIRJOEL EXAM SOLUTIONS
12/3/2024 11:27AM



MEDS 530A Pathology Final Exam
Questions With Correct Answers


A 60-year-old man who had generalized atherosclerosis died 24 hours after having a stroke. A

cerebral infarct was found at autopsy. Necrosis of the brain is classified as - answer✔Brain

infarcts are characterized by liquefactive necrosis.

A 30-year-old woman who had leukemia was treated with bone marrow transplantation. She

developed a skin rash that was interpreted as a sign of a graft-versus- host reaction. A skin

biopsy was performed. In the epidermis, there were scattered dead epidermal cells that had

rounded contours and pyknotic nuclei. This form of cell death is caused by - answer✔Graft-

versus-host-induced cell death in the epidermis is a form of apoptosis. It is mediated by capsizes

and other enzymes of the suicide pathway of "programmed cell death.


Uptake of bacteria into the cytoplasm of neutrophilic leukocytes is called - answer✔Uptake of

bacteria and other exogenous particulate material into the phagosomes is called phagocytosis.

A 90-year-old man died in a nursing home. During the past 10 years, he was unable to care for

himself and was mentally incoherent. He had no memory and could not hold a conversation. He

was unaware of his surroundings. At autopsy, the brain showed signs of Alzheimer disease, and

there were neurons containing numerous neurofibrillary tangles. These cytoplasmic structures

, ©SIRJOEL EXAM SOLUTIONS
12/3/2024 11:27AM


are formed from which component of the neurons? - answer✔Neurofibrillary tangles are

composed of microtubule-associated proteins and neurofilaments, which form the cytoskeleton

of nerve cells.

Continuous expression of the gene for atrial natriuretic factor in the myocardial cells of the left

ventricle is typically a consequence of - answer✔Atrial natriuretic factor (ANF) is produced

during fetal life in both the atrial and ventricular cells of the heart. After birth, the ANF gene

remains active only in the atrium, but can be activated in ventricular cells undergoing

hypertrophy. Arterial hypertension is the most common cause of ventricular hypertrophy.

A 28-year-old man was found to have cirrhosis of the liver and pulmonary emphysema. The liver

cells contained globular inclusions in their cytoplasm, which by electron microscopy are shown

to be located inside the - answer✔The clinical history (i.e., the concurrence of cirrhosis and

pulmonary emphysema) suggests that this young man has 1-antitrypsin (AAT) deficiency. The

cytoplasmic globules in the liver cells represent misfolded AAT, which cannot be excreted from

the liver cells and remains inside the liver cells in the dilated cisterns of the rough endoplasmic

reticulum.


Ubiquitin-proteasome degradation of plasma proteins is opposed by - answer✔Insulin can

oppose ubiquitin-proteasome degradation of plasma proteins, whereas all other hormones and

mediators of inflammation listed here accelerate it.

A 60-year-old obese man was admitted to the hospital for treatment of alcoholism. He has

diabetes mellitus. A liver biopsy was performed, and the specimen showed that the liver cells

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