A woman wants to donate blood. Her physical examination reveals the
following: weight—110 pounds, pulse—73, blood pressure—125/75,
hematocrit—35. Which of the following applies to the prospective donor?
a. Exclusion due to high pulse
b. Exclusion due to low weight
c. Exclusion due to low hematocrit
d. Exclusion due to high blood pressure
e. The donor is acceptable Answer - Exclusion due to low hematocrit
An otherwise healthy person wants to donate blood. However, the person
weighs only 95 pounds. What is the allowable amount of blood that can be
drawn, not counting blood for the pilot tubes?
a. 367 mL
b. 378 mL
c. 400 mL
d. 425 mL
e. 454 mL Answer - 454 ml
Which of the following donors would be deferred indefinitely?
a. History of syphilis
b. History of gonorrhea
c. Accutane treatment
,d. Recipient of human growth hormone
e. Recipient of a vaccination Answer - Recipient of human growth hormone
Although cryoprecipitate is commonly used for treatment of
hypofibrinogenemia and hemophilia A, it contains other blood proteins useful
in the treatment of coagulopathies. Which of the following is not found in
cryoprecipitate?
a. Fibronectin
b. Factor XIII
c. Factor VIII:vW
d. Antithrombin III
e. Factor VIII:C Answer - Antithrombin III
The addition of adenine in the CPDA-1 formulation aids in:
a. Binding calcium
b. Maintaining ATP levels for red cell viability
c. Maintaining platelet function in stored blood
d. Reducing the plasma K+ levels during storage
e. Maintaining 2,3-DPG levels for oxygen release to the tissues Answer -
Maintaining ATP levels for red cell viability
A satellite bag containing 250 mL of fresh plasma is selected for quality control
of cryoprecipitate production. Cyro is prepared according to standard operating
procedures.
The final product has a total volume of 10 mL. The factor VIII assays are 1
IU/mL before and 9 IU/mL after preparation.
What is the percent yield of factor VIII in the final cryoprecipitate?
, a. 11%
b. 25%
c. 36%
d. 52%
e. 80% Answer - 36%
A satellite bag containing 250 mL of fresh plasma is selected for quality control
of cryoprecipitate production. Cyro is prepared according to standard operating
procedures.
The final product has a total volume of 10 mL. The factor VIII assays are 1
IU/mL before and 9 IU/mL after preparation.
Does this product meet AABB standards for cryo production?
a. Yes
b. No, the percent recovery is too low
c. No, the final factor VIII level is too low
d. Data are insufficient to calculate
e. No such standard exists Answer - Yes (*The FDA mandates a single unit of
Cryoprecipitate must contain
fibrinogen
≥ 150 mg/unit
and factor VIII ≥ 80 IU/unit)
A centrifuge used for platelet preparation has
been returned after major repair. A unit of whole
blood (450 mL; platelet count 200,000/ul_) is
selected for calibration of platelet production.
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