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Pharm Tox Final Exam Questions with Correct Answers (A Graded)
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Pharm Tox Final Exam Questions with Correct Answers (A Graded)
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Pharm Tox Final Exam Questions withCorrect Answers (A Graded)
Which of the following statements is TRUE about the pharmacological management of
PD A. development of dyskinesias only occurs with the use of L-dopa
B. L-dopa response may be altered in patients that carry a PM phenotype of
CYP2D6 C. Apomorphine is the drug of choice to rescue from off periods D. all the
above - ANSWER C
Which of the following is true about dopaminergic psycho-stimulants A.
amphetamines and cocaine are equivalent on their therapeutic areas
B. amphetamine generates a differential effect in neurotransmitters that is related
to amphetamine dose
C. the addictive characteristics of psychostimulants are related to activation of the
neurons from VTA to the striatum
D. Cocaine main effect is due to its inhibition of the DA uptake transporter while amphetamine
doesn't interact with this transporter - ANSWER B
One of the following statements about Alzheimer's disease is FALSE
A. most therapeutic approaches in AD treatment are aimed to increase ACh levels in brain
,B. Carrying two copies of the Apo E4 gene is considered to be a risk factor in the development
of AD
C. Memantine helps in AD by regulating the activity of glutamate
D. There are no major risk factors with the use of antipsychotics in AD patients - ANSWER D
This drug is NOT approved for the treatment of alcohol addiction
A. topiramate
B. naltrexone
C. methadone
D. disulfiram
E. acamprosate - ANSWER C
Increased activity of secretases alters brain levels of
A. alpha synuclein
B. Huntingtin
C. beta-amyloid
D. Tau - ANSWER C
Genetic polymorphisms in CYP2D6 will not impact the bioavailability of this drug used in
the treatment of AD
A. rivastigmine
B. donepezil
C. galantamine
D. reserpine - ANSWER A
This drug has been useful to generate an aversive reaction to alcohol consumption
A. naltrexone
B. acamprosate
, C. disulfiram
D. bupropion - ANSWER C
Which of the of the following is an effect of amphetamine
A. prevention of sleep
B. mydriasis
C. increased heart rate
D. all the above - ANSWER D
This metabolic product of serotonin is a pineal gland hormone
A. epinephrine
B. DA
C. melatonin
D. tyrosine - ANSWER C
The objectives of addiction treatment are
A. help the individual stop using drugs
B. maintain a drug-free lifestyle
C. achieve productive functioning in the family, at work, and in society
D. all the above - ANSWER D
The drug varenicline is used to treat tobacco addiction because
a. its limits the levels of nicotine that cross the BBB
b. it binds to nicotine reducing its affinity for the nicotine receptor
c. it competes with nicotine for the nicotinic receptor
d. it blocks the release of acetyl choline limiting activity in nicotinic receptors - ANSWER C
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