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NU 578 Spring 2017 Unit 4 Study Guide

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NU 578 Spring 2017 Unit 4 Study Guide Treatments for Hypothyroidism - Answer-Levothyroxine (T4), Liothyronine (T3), Liotrix, Thyroid (Desiccated) Levothyroxine (T4) - Answer-Drug of choice for patients who require thyroid hormone replacement. Absorption is reduced by food. Most of the does is c...

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  • October 16, 2024
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NU 578 Spring 2017 Unit 4 Study Guide

Treatments for Hypothyroidism - Answer✔✔-Levothyroxine (T4), Liothyronine (T3), Liotrix,

Thyroid (Desiccated)


Levothyroxine (T4) - Answer✔✔-Drug of choice for patients who require thyroid hormone

replacement. Absorption is reduced by food. Most of the does is converted to T3. Highly bound

to protein and half life is about 7 days. Used for cretinism, myxedema coma, simple goiter, and

primary hypothyroidism in adults and children. With overdose s/s of thyroid toxicosis may

result. Chronic overdose is associated with accelerated bone loss and increased risk of atrial

fibrillation, especially in older adults.


What are the signs and symptoms of thyrotoxicosis? - Answer✔✔-Tachycardia, angina, tremor,

nervousness, insomnia, hyperthermia, heat intolerance, and sweating.


Drugs that reduce Levothyroxine Absorption - Answer✔✔-Histamine (H2) receptor blockers like

cimetidine (Tagamet), Proton pump inhibitors like lansoprazole (Prevacid), Sucralfate (Carafate),

Cholestyramine (Questran), Colestipol (Colestid), Aluminum-containing antacid, Calcium

supplements, Iron supplements, Magnesium salts, Orlistat (Xenical). Separate administration of

(blank) by 4 hours .




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, EMILLECT 2024/2025 ACADEMIC YEAR ©2024 EMILLECT. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER, 2024


Drugs that accelerate Levothyroxine Metabolism - Answer✔✔-Phenytoin, Carbamazepine

(Tegretol, Carbatrol), Rifampin (Rifadin), Sertraline (Zoloft) and Phenobarbital. Patient's may

need an increase in (blank) medication if taking these drugs.


What happens when Levothyroxine and Warfarin are taken together ? - Answer✔✔-

Levothyroxine (blank) the degradation of vitamin K-dependent clotting factors which results in

(blank) effects of warfarin. Dosage of Warfarin may need to be (blank)


a.) accelerates, enhanced, reduced


b.) slows, decreased, increased


c. No change in Warfarin


answer is a.


What happens when Levothyroxine and Catecholamines are taken together? - Answer✔✔-

Thyroid hormones (blank) cardiac responsive to catecholamines (epinephrine, dopamine,

dobutamine) thereby (blank) the risk of catecholamine induced dysrhythmias.


a.) decrease, reducing,


b. increase, increasing


c. No change in medication


answer is b.


Levothyroxine can (blank) requirements for insulin and digoxin and dosages may need to be

(blank) - Answer✔✔-a.) decrease, reduced

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