1. Nurse jpractitioner prescriptive jauthority jis jregulated jby:
A. The jNational jCouncil jof jState jBoards jof jNursing
B. The jU.S. jDrug jEnforcement jAdministration
C. The jState jBoard jof jNursing jfor jeach jstate
D. The jState jBoard jof jPharmacy
ANS: j C PTS: j j1
2. The jbenefits jto jthe jpatient jof jhaving jan jadvanced jpractice jregistered jnurse j(APRN)
jprescriber jinclude:
A. Nurses jknow jmore jabout jpharmacology jthan jother jprescribers jbecause jthey jtake
jit jboth jin jtheir jbasic jnursing jprogram jand jin jtheir jAPRN jprogram.
B. Nurses jcare jfor jthe jpatient jfrom ja jholistic japproach jand jinclude jthe jpatient
jin jdecision-making jregarding jtheir jcare.
C. APRNs jare jless jlikely jto jprescribe jnarcotics jand jother jcontrolled jsubstances.
D. APRNs jare jable jto jprescribe jindependently jin jall jstates, jwhereas ja
jphysician’s jassistant jneeds jto jhave ja jphysician jsupervising jtheir jpractice.
ANS: j B PTS: j j1
3. Clinical jjudgment jin jprescribing jincludes:
A. Factoring jin jthe jcost jto jthe jpatient jof jthe jmedication jprescribed
B. Always jprescribing jthe jnewest jmedication javailable jfor jthe jdisease jprocess
C. Handing jout jdrug jsamples jto jpoor jpatients
D. Prescribing jall jgeneric jmedications jto jcut jcosts
ANS: j A PTS: j j1
4. The jprocess jfor jchoosing jan jeffective jdrug jfor ja jdisorder jincludes:
A. Asking jthe jpatient jwhat jdrug jthey jthink jwould jwork jbest jfor jthem
B. Consulting jnationally jrecognized jguidelines jfor jdisease jmanagement
C. Prescribing jmedications jthat jare javailable jas jsamples jbefore jwriting ja jprescription
D. Following jU.S. jDrug jEnforcement jAdministration jguidelines jfor jprescribing
ANS: j B PTS: j j1
5. Nonintentional jnonadherence jof jdrug jtherapy jmay joccur jdue jto:
A. Belief jthat jmedication jdoes jnot jwork
B. Adverse jdrug jreactions
C. Chronic jconditions jthat jrequire jdaily jtherapy
D. Forgetfulness jor jdistraction
ANS: j D PTS: j j1
, Woo 1
Pharmacotherapeutics for APN Prescribers, 6e Ch02
1. A jpatient’s jnutritional jintake jand jlaboratory jresults jreflect jhypoalbuminemia. jThis jis
jcritical jto jprescribing jbecause:
A. Distribution jof jdrugs jto jtarget jtissue jmay jbe jaffected.
B. The jsolubility jof jthe jdrug jwill jnot jmatch jthe jsite jof jabsorption.
C. There jwill jbe jless jfree jdrug javailable jto jgenerate jan jeffect.
D. Drugs jbound jto jalbumin jare jreadily jexcreted jby jthe jkidneys.
ANS: j A PTS: j j1
2. Drugs jthat jhave ja jsignificant jfirst-pass jeffect:
A. Must jbe jgiven jby jthe jenteral j(oral) jroute jonly
B. Bypass jthe jhepatic jcirculation
C. Are jrapidly jmetabolized jby jthe jliver jand jmay jhave jlittle, jif jany, jdesired jaction
D. Are jconverted jby jthe jliver jto jmore jactive jand jfat-soluble jforms
ANS: j C PTS: j j1
3. The jroute jof jexcretion jof ja jvolatile jdrug jwill jlikely jbe jthe:
A. Kidneys
B. Lungs
C. Bile jand jfeces
D. Skin
ANS: j B PTS: j j1
4. A jmajor jdisadvantage jto jIV jadministration jis jthat:
A. First-pass jmetabolism jis jeliminated.
B. Needles jand jsterility jare jrequired.
C. Absorption jof jthe jdrug jcannot jbe jslowed jafter jadministration.
D. It jis jsignificantly jmore jexpensive jthan jother jroutes.
ANS: j C PTS: j j1
5. The jnurse jpractitioner j(NP) jchooses jto jgive jcephalexin jevery j8 jhours jbased jon jknowledge
jof jthe jdrug’s:
A. Propensity jto jgo jto jthe jtarget jreceptor
B. Biological jhalf-life
C. Pharmacodynamics
D. Safety jand jside jeffects
ANS: j B PTS: j j1
6. Deferasirox jis ja jchelating jagent jused jto jtreat jiron joverload jby jbinding jiron jto
jrender jit jbiologically jinactive. jThis jis jbest jcharacterized jas ja(n):
, Woo 2
Pharmacotherapeutics for APN Prescribers, 6e Ch02
A. Nonreceptor jmechanism
B. Partial jagonist
C. Full jagonist
D. Noncompetitive jantagonist
ANS: j A PTS: j j1
7. The jpoint jin jtime jon jthe jdrug jconcentration jcurve jthat jindicates jthe jfirst jsign jof ja
jtherapeutic jeffect jis jthe:
A. Minimum jadverse jeffect jlevel
B. Peak jof jaction
C. Onset jof jaction
D. Therapeutic jrange
ANS: j C PTS: j j1
8. Phenytoin jrequires jthat ja jtrough jlevel jbe jdrawn. jPeak jand jtrough jlevels jare jdone:
A. When jthe jdrug jhas ja jwide jtherapeutic jrange
B. When jthe jdrug jwill jbe jadministered jfor ja jshort jtime jonly
C. When jthere jis ja jhigh jcorrelation jbetween jthe jdose jand jsaturation jof jreceptor jsites
D. To jdetermine jif ja jdrug jis jin jthe jtherapeutic jrange
ANS: j D PTS: j j1
9. A jlaboratory jresult jindicates jthat jthe jpeak jlevel jfor ja jdrug jis jabove jthe jminimum
jtoxic jconcentration. jThis jmeans jthat jthe:
A. Concentration jwill jproduce jtherapeutic jeffects.
B. Concentration jwill jproduce jan jadverse jresponse.
C. Time jbetween jdoses jmust jbe jshortened.
D. Duration jof jaction jof jthe jdrug jis jtoo jlong.
ANS: j B PTS: j j1
10. Drugs jthat jare jreceptor jagonists jmay jdemonstrate jwhat jproperty?
A. Irreversible jbinding jto jthe jdrug jreceptor jsite
B. Up-regulation jwith jchronic juse
C. Desensitization jor jdown-regulation jwith jcontinuous juse
D. Inverse jrelationship jbetween jdrug jconcentration jand jdrug jaction
ANS: j C PTS: j j1
11. Drugs jthat jare jreceptor jantagonists, jsuch jas jbeta jblockers, jmay jcause:
A. Down-regulation jof jthe jdrug jreceptor
B. An jexaggerated jresponse jif jabruptly jdiscontinued
C. Partial jblockade jof jthe jeffects jof jagonist jdrugs
D. An jexaggerated jresponse jto jcompetitive jdrug jagonists
ANS: j B PTS: j j1
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