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MDSC 321 Exam Study Guide
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MDSC 321 Exam Study GuideCardinal signals of inflamation - Answer Celsus:
Rubor= redness
Tumor= swelling
Calor= heat
Dolor= pain
Galen:
Functio Laesa= loss of function
Inflamation is what kind of immune response? - Answer Inflammation is an innate,
non-specific response which brings leukocytes and plasma to areas of infection by
increaseing fluids (humoral).
When and how did the first "vaccine" work? - Answer In 12th century, Chinese and the
Turks ground up dried small pox pustules and either inhaled them or rubbed them into
cuts respectively.
Robert Koch was influential to the world of immunology, why? - Answer -discovered that
microbes cause wounds to go septic
-identified bacteria which causes TB and Cholera
-4 postulates:
1. organism needs to be present only in diseased animals
2. organism should be culutred away from the animal body
3. when animals are given the microbe, they ought to show signs of disease
4. organism should be reisolated from experimental animals and repeat the process to
have the same results
What did Louis Pasteur contribute? - Answer -pretreatment with attenuated Cholera
bacteria conferred proteins to chickens
-Anthrax vaccine (100% with it lived, 100% without it died)
-developed rabies vaccine for dogs, but also used it to treat a person
von Behring led to the concept of humoral immunity, what else did he contribute? -
Answer Found if you transfer a serum from a immunized animal, it could lead to
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