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What neurochemical abnormality is most consistently described in Alzheimer
disease of moderate severity. - ANSWER✔✔Decreased choline acetyltransferase
activity
Which of the following sources of pain is thought to have a primarily central (non-
nociceptive) mechanism?
a) cancer pain
b) fibromyalgia
c) osteoarthritis
d) diabetic neuropathy
e) postherpetic neuralgia - ANSWER✔✔b) fibromyalgia
A patient presents with mild memory impairment, tearfulness, insomnia, and blurry
vision. The patient acts as if blind, cannot locate objects in the visual field, has left-
right disorientation and alexia, and misses objects when instructed to reach for
them. The patient only identifies a single object in a drawing of overlapping
objects. Despite requiring prompts to visually follow objects, cranial nerves, motor
function, reflexes, and movement and color detection are otherwise intact. What is
the most likely cause of the visual disturbance? - ANSWER✔✔Cerebral infarct
Variable phenotypic expression of 15q13 deletion depends on whether the
encoding gene is
derived from the father or the mother. This phenomenon is commonly referred to
as - ANSWER✔✔Genomic imprinting
A patient hospitalized for burns sustained in a house fire one week prior is
experiencing recurrent nightmares and frequent, intrusive memories about the fire
accompanied by concern that the patient seems depressed, is sleeping poorly and
startles when someone enters the room without knocking. On exam, the patient is
distracted, sometimes irritable, and has labile affect. What is the most likely
diagnosis? - ANSWER✔✔Acute stress disorder
What is an example of epigenetic gene regulation? - ANSWER✔✔Addition of
methyl group to a histone around which DNA is coiled.
,What sex hormone is most responsible for sexual differentiation in fetal brain
development? - ANSWER✔✔Testosterone (causes brain/body to be masculinized
and defeminized)
What psychiatric disorder occurs most frequently with secondary enuresis? -
ANSWER✔✔ADHD
The psychiatrist is concerned about a colleague's behavior and notifies the State's
physician health program, which conducts an intervention. The physician should
be referred for professional evaluation/treatment in which scenario?
A) drinks wine with diner
B) has experienced depression and been hospitalized in past
C) has bipolar disorder and is euthymic/med compliant
D) uses cocaine occasionally but not habitually, on days off, negative utox
E) aggressive toward patients on 3 different occasions during ED shifts -
ANSWER✔✔E
Abnormalities in which of the following components of the neurological
examination would indicate cerebellar dysfunction? - ANSWER✔✔Rapid
alternating movements
Excessive activation of which of the following receptors is thought to contribute to
cell death in Alzheimer disease? - ANSWER✔✔NMDA
In behavior mastery training, which of the following techniques teaches individuals
with sexual addiction to identify factors that increase the likelihood of
symptomatic sexual behavior? - ANSWER✔✔Risk management
A patient has been prescribed a second-gen antipsychotic for just over a year.
Since starting the medication, her libido is markedly lower, and she has
experienced irregular menstrual cycles. Which lab test would have greatest
diagnostic value at this point? - ANSWER✔✔Prolactin
A 58 year old patient develops progressive weakness and tingling two weeks after
receiving a vaccination. Examination reveals weakness and decreased sensation in
the legs, as well as absent DTRs in arms and legs. Imaging of the brain and spine is
, normal. Which test will confirm the most likely diagnosis? - ANSWER✔✔Nerve
conduction studies
Which of the following is among the first steps taken by a public school to address
a student's difficulty being successful academically? - ANSWER✔✔Initiate a
response to intervention plan
Which of the following nuclei of the hypothalamus is the major site for
Neuropeptide Y synthesis? - ANSWER✔✔Arcuate nucleus
Which type of group therapy encourages high intragroup dependence and less
group leader dependence? - ANSWER✔✔Transactional
Which mechanism is the most likely cause of anosmia in patients infected with
COVID19? - ANSWER✔✔Direct viral involvement of the nasal epithelium
An argumentative 10 year old who displays persistent anger outbursts,
vindictiveness, and deliberately annoys adults most likely has what disorder? -
ANSWER✔✔Oppositional defiant disorder
What outcome has been demonstrated to improve as a result of peer support
services in the treatment of people with mental illness? - ANSWER✔✔Social
functioning
Electroconvulsive therapy is indicated for which of the following conditions?
A) Dissociative fugue
B) Serotonin syndrome
C) Intermittent explosive disorder
D) OCD
E) NMS - ANSWER✔✔E) NMS
Which white matter tracts connects the temporal and orbitofrontal cortices? -
ANSWER✔✔Uncinate fasiculus
Cingulum - ANSWER✔✔Connects frontal, temporal, and parietal lobes and also
subcortical nuclei to cingulate gyrus
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